Epigenetics in Health and Disease part B

Dr Vijai Singh is a Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 chapters, 15 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University. Dr. Indra Mani is an Assistant Professor in the Department of Microbiology, Gargi College, University of Delhi (DU), New Delhi, India. He received M.Sc. in Microbiology from Bundelkhand University (BU), Jhansi, UP, India and Ph.D. in Biochemistry from Banaras Hindu University (BHU), Varanasi, UP, India. He completed postdoctoral training in the Department of Physiology, School of Medicine, Tulane University, New Orleans, USA. He has also worked as a Senior Research Officer (SRO) in the Department of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, India. He has more than 10 years of research and teaching experience in Microbiology, Molecular Genetics, Cell Signaling, and Bioinformatics. He has published 49 articles in peer reviewed journals and 22 book chapters. He has presented several papers in the different national and international conferences. He has extensive experience in fluorescence/confocal microscopy, receptor internalization, trafficking and signaling, molecular cytogenetics, microbial characterization, and in silico analysis. He serves as a reviewer of peer-reviewed journals and also a member of national and international societies.

Preface

Vijai Singh and Indra Mani

1. Applications of bioinformatics in epigenetics

Ragini, Sakshi, Indra Mani and Vijai Singh

2. CRISPR-dCas9 systems for epigenetic editing for therapeutic applications

Gargi Bhattacharjee, Nisarg Gohil, Deepak Siruka, Khushal Khambhati, Rupesh Maurya, Suresh Ramakrishna, Dinh-Toi Chu and Vijai Singh

3. Epigenetics control of heredity

Akanksha Singh Kachhawaha, Sarita Mishra and Anand Krishna Tiwari

4. Epigenetics in renal diseases

Sakshi, Ragini, Ashok Saini, Chaitenya Verma and Indra Mani

5. Epigenetics in cancer development, diagnosis and therapy

Dinh-Toi Chu, Anh-Dao Ngo and Chia-Ching Wu

6. Microbiota and epigenetics: Health impact

Taruna Ahrodia, Bharti Kandiyal and Bhabatosh Das

7. Histone deacetylase (HDACs) inhibitors: Clinical applications

Kumar D. Shanmukha, Harikrishnareddy Paluvai, Santosh K. Lomada, Mahesh Gokara and Suresh K. Kalangi

8. Early epigenetic markers for precision medicine

Sibi Raj and Dhruv Kumar

9. Epigenetics for neurological diseases

Ozasvi R. Shanker, Sonali Kumar, Aparna Banerjee Dixit, Jyotirmoy Banerjee, Manjari Tripathi and P. Sarat Chandra

10. Epigenetic regulons in Alzheimer's disease

Mahima Raval, Sarita Mishra and Anand Krishna Tiwari

11. Epigenetics in epilepsy

Sonali Kumar, Ozasvi R. Shanker, Jyotirmoy Banerjee, Manjari Tripathi, P. Sarat Chandra and Aparna Banerjee Dixit