Genetically Modified and other Innovative Vector Control Technologies

Brij Kishore Tyagi Born 23rd July 1951, Dr. Brij Kishore Tyagi (PhD 1979) has become emeritus in 2013, with two years’ extension till 2015, as Scientist ‘G’ & Director-in-Charge from the ICMR-Centre for Research in Medical Entomology, Madurai, after distinguished service in medical entomology and vectorborne diseases in most of States and UTs in the country. He has since continued as the Visiting Professor in various universities (2016–2019) and currently is the Advisor, VIT Univ., Vellore (TN) as well as the International Consultant for a BCIL-FAO Sri Lanka Project on GMO Biosafety (2019–2021). He has to his credit >640 scientific titles, besides 37 books, incl. a WHO Training Manual on GM vectors (2015). Recipient of the prestigious WHO-TDR First Prize in worldwide competition (1995) and the ICMR’s Dr. MOT Iyengar Memorial Award (2008), he is the Founding President of the Society of Medical Arthropodology (www.soma16.org). He has participated in preparing OECD’s Consensus Document on Aedes aegypti (2018), is Chairman, RCGM-DBT’s Subcommittee for the formulation of biosafety guidelines to conduct and monitor research trials (CRTs) on genetically engineered mosquitoes, and an Expert Member of the DBT-RCGM Committee on GM insects.

Chapter 1. Arthropod disease vectors: Genetic manipulations and other innovative technologies for mosquito control, with emphasis on eco-bio-social considerations.- Chapter 2. Field trials of gene drive mosquitoes: Lessons from releases of genetically sterile males and Wolbachia-infected mosquitoes.- Chapter 3. Genetic improvements to the Sterile Insect Technique (SIT) for the control of mosquito population.- Chapter 4. Advances in Aedes mosquito vector control strategies using CRISPR/Cas9.- Chapter 5. Evaluation of transgenic Aedes aegypti L. strain in India – A friendly mosquito.- Chapter 6. Three decades of malaria vector control in Sudan: The plausible role of Sterile Insect Technique (SIT).- Chapter 7. Perspectives into genetic manipulations for control of dengue vector (Aedes aegypti Linnaeus, 1762) with reference to progress in Indian experiments.- Chapter 8. Overcoming the dengue challenges using Innovative Strategy: The Malaysian experience.- Chapter 9. Malaria control in Africa using vector genetic manipulation.- Chapter 10. RNA interference based technologies to control dengue vector mosquitoes.- Chapter 11. Wolbachia: Biological control strategy against arboviral diseases.- Chapter 12. Wolbachia endosymbiont and mosquito vectors, with emphasis on lymphatic filariasis elimination.- Chapter 13. Laboratory biosafety in handling genetically modified mosquitoes.- Chapter 14. Novel diagnosis and control of arboviruses.- Chapter 15. Long lasting insecticidal nets: an evidence-based technology for malaria vector control and future perspectives.- Chapter 16. Novel development of an indigenous Long Lasting Insecticide Bednet (LLIN) to defend against the hematophagous arthropods.- Chapter 17. Nanotechnology and Polymer Science: A novel approach in vector control.- Chapter 18. Nano-sized emulsion system: A comprehensive tool towards controlling vectormosquito Populations.- Chapter 19. DEPA (- N, N-Diethyl Phenyl Acetamide) –  Commercial journey of India’s first indigenous mosquito repellent with novel properties.- Chapter 20. Remote Sensing and Geographic Information Technology in novel vector control.- Chapter 21. Social and ecological factors responsible for changing habitat of Kala-azar vector (Phlebotomus argentines) and its control through locally innovated environment-friendly technology.- Chapter 22. Safety assessment of novel genetic technologies for vector control: National and international perspectives.- Chapter 23. Measuring public attitudes to releases of transgenic mosquitoes for disease control, with special reference to dengue and malaria.- Chapter 24. Safe application of genetically modified mosquito (GMM) to combat dengue and chikungunya depends on socio-economic status and social acceptance in the developing countries: A comprehensive analysis.- Chapter 25. Experiences and outcomes from a worldwide training programme on genetically modified vectors (GMVs) related biosafety for human health and the environment.-