Molecular Diagnosis and Targeting for Gynecologic Malignancy
Springer Verlag, Singapore
978-981-336-015-0 (ISBN)
Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response.
Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.
Seiji Isonishi Department of Obstetrics and Gynecology The Jikei University School of Medicine Minato-ku, Tokyo, Japan Yoshihiro Kikuchi Department of Gynecology Ohki Memorial Kikuchi Cancer Clinic for Women Tokorozawa, Japan
1 Cancer Stem Cells in gynecologic cancer.- 2 Patient-derived xenograft models in gynaecological malignancies.- 3 Cancer genomic profiling of gynecological malignancies by Todai OncoPanel, a twin DNA and RNA panel.- 4 Investigating the molecular carcinogenesis of ovarian high-grade serous cancer.- 5 The role of G protein-coupled receptor signaling in gynecologic malignancy.- 6 Tailor-made therapy according genetic alteration in epithelial ovarian cancers.- 7 Signaling and drug resistance.- 8 Molecular analysis in endometrial carcinoma.- 9 Molecular Landscape in Ovarian Clear Cell Carcinoma.- 10 Molecular pathology and clinicopathological significance of endometrial carcinoma.- 11 Novel approach for therapeutics of cervical cancer based on HPV-associated carcinogenesis at the cervix.- 12 Hereditary gynecological malignancy and molecular features.
Erscheinungsdatum | 11.03.2022 |
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Reihe/Serie | Current Human Cell Research and Applications |
Zusatzinfo | 24 Illustrations, color; 2 Illustrations, black and white; VIII, 165 p. 26 illus., 24 illus. in color. |
Verlagsort | Singapore |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Gynäkologie / Geburtshilfe |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Schlagworte | Cell Biology • drug resistance • genomic analysis • Gynecologic tumor • signaling pathway • Tumor evolution |
ISBN-10 | 981-336-015-1 / 9813360151 |
ISBN-13 | 978-981-336-015-0 / 9789813360150 |
Zustand | Neuware |
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