Organic Cation Transporters in the Central Nervous System

Buch | Hardcover

XII, 328 Seiten

2021 | 1st ed. 2021
Springer International Publishing (Verlag)
978-3-030-82983-4 (ISBN)

Artikel merken

Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics.
The chapter, "General Overview of Organic Cation Transporters in Brain", of this book is available open access under a CC BY 4.0 license at link.springer.com

General Overview of Organic Cation Transporters in Brain.- Organic Cation Transporter Expression and Function in the CNS.- Genetic and Epigenetic Regulation of Organic Cation Transporters.- Experimental Methods for Investigating Uptake 2 Processes In Vivo.- Substrates and inhibitors of OCTs and PMAT and therapeutic implications.- Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications.- Organic Cation Transporters in Brain Catecholamine Homeostasis.- The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances.- Organic Cation Transporters in Psychiatric Disorders.- Organic Cation Transporters and Nongenomic Glucocorticoid Action.- Brain Plasma Membrane Monoamine Transporter in Health and Disease.- Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications.- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery.

Erscheinungsdatum	28.10.2021
Reihe/Serie	Handbook of Experimental Pharmacology
Zusatzinfo	XII, 328 p. 70 illus.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	666 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Pharmazie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
Schlagworte	monoamine homeostasis • Organic Cation Transporter (OCT) • plasma membrane monoamine transporter (PMAT) • psychiatric disorders • Substance use disorders • therapeutics
ISBN-10	3-030-82983-9 / 3030829839
ISBN-13	978-3-030-82983-4 / 9783030829834
Zustand	Neuware