Toxicology of Organophosphate Poisoning

lt;p>Prof. Tanu Jindal completed her PhD in Ecotoxicology from Department of Zoology, University of Delhi in 1999. She is Group Additional Pro Vice Chancellor (R&D) and the Director of Amity Institute for Environmental Toxicology, Safety and Management (AIETSM) and Amity Institute of Environmental Sciences (AIES) at Amity University, Noida., UP, India. She is responsible for PhD, MSc. and B.Sc Environmental Science courses to promote environmental research and studies with syllabus covering important and current area of environmental science. She has filed six patents on lysimetric-device, apparatus to estimate the loss of xenobiotics by volatilization and mineralization, natural pesticide, photochemical method to dispose of dilute pesticide waste and cost-effective water testing kit.  She has completed projects on Yamuna, Hindon, Ghagghar River ad groundwater contamination through pesticides, MoEF&CC; Contamination of soil and groundwater through leaching of drains in Delhi, MoES; Groundwater contamination of Chlorpyrifos in soils at different pH with CWRDM, DST; Environmental monitoring studies at Antarctica- NCAOR, Goa; Impact of Electro Magnetic Radiation- DST. Her recent initiatives are projects on Development of Lysimeter -DST; Air Pollution Monitoring through CAAQMS-UPPCB; Development of Emission Factors, CPCB. Establishment of the Pesticide Referral Laboratory and MRL fixation of pulses and spices were her research endeavors at ICAR. Her expertise area is ISO-17025, GLP-studies, radio and stable isotope tracer techniques, GCMS and LCMS studies etc. She taught Pesticides Chemistry and Toxicology in Delhi University for 7 years to MSc students. She holds membership of eminent scientific societies. She has travelled extensively nationally and internationally presenting papers and has publications in referred journals of high impact factor. She has published more than 38 papers in reputed journals and has been serving as an editorial board member of repute.  Editor of The Year Award 2017 by MTRES, Excellence in Research and Teaching Award 2017 by National Environmental Science Academy, prestigious Scientist of the year Award - 2015, Environmentalist of the Year Award-2014 by NESA, New Investigator Award presentation at ACS, DST Young Scientist Award Project are to her credit. She has received travel awards from CSIR, DST & INSA.

Dr. Anuj Ranjan is Assistant Professor at Amity Institute of Environmental Toxicology, Safety and Management, Amity University, Noida, UP, India. His research area is structural bioinformatics, target characterization, molecular docking and simulation, and predictive toxicology. He has guided graduate and post graduate students of Environmental Health Science students and is currently the supervisor of two Ph.D. Students. He has received awards from CSIR, Govt. of India, and the American Chemical society (2016), and has presented his work at North American Chemical residue workshops (NACRW) (2017) in Naples, Florida, USA. 

Chapter 1: Overview of organophosphate compounds.- Chapter 2: Toxicology of Organophosphate poisoning in humans.- Chapter 3: Enzymatic Targets of organophosphates.- Chapter 4: Computational insights of human acetylcholinesterase inhibition.- Chapter 5: New insights in Prophylactic approaches of human poisoning.- Chapter 6: Management of human Organophosphate poisoning.- Chapter 7: Summary.