Donor-Acceptor Cyclopropanes in Organic Synthesis

Buch | Hardcover
464 Seiten
2024 | 1. Auflage
Wiley-VCH (Verlag)
978-3-527-34987-6 (ISBN)
149,00 inkl. MwSt
Doner-Acceptor Cyclopropanes (DACs) play an essential role in organic reactions and belong to the toolbox of synthetic chemistry. This book covers comprehensively the chemistry and applications of this compound class and is indispensable for every scientist working in this area.

P. Banerjee has obtained his Doctoral degree from National Chemical Laboratory (NCL) under the supervision of Prof. Ganesh Pandey, Pune, and later worked with Prof. Gais at RWTH-Aachen, Germany as DFG postdoctoral fellow from 2005 to 2007. Then he moved to Purdue University, USA, where he worked with Prof. Fuchs before joining IIT Ropar as an assistant professor in 2010 at the Department of chemistry. He was promoted to associate professor in 2016. He has extensive research experience in pericyclic reactions with particular emphasis on cycloaddition reactions, asymmetric catalysis, and synthesis of medicinally significant molecules. In his independent research carrier, he has also worked extensively on the reactivity of different strained rings towards cycloaddition reactions to synthesize pharmaceutically important heterocyclic compounds. A. T. Biju received his PhD (2006) under the guidance of Dr Vijay Nair at the CSIR-NIIST (Formerly RRL), Trivandrum, India. Subsequently, he has been a post-doctoral fellow with Prof. Tien-Yau Luh (National Taiwan University) and an AvH fellow with Prof. Frank Glorius (WWU Münster, Germany). In June 2011, he began his independent research career at the CSIR-NCL, Pune. Since June 2017, he has been an Associate Professor in the Department of Organic Chemistry, Indian Institute of Science, Bangalore. His research focuses on the development of transition-metal-free carbon-carbon and carbon-heteroatom bond-forming reactions using aryne chemistry and NHC organocatalysis, and their application in organic synthesis. He is the Editor of J. Heterocyclic Chem., and the Advisory Board of Org. Chem. Front. And Asian J. Org. Chem.

Preface
1) Introduction to the Chemistry of Donor-Acceptor Cyclopropanes: A Historical and Personal Perspective
2) Understanding Reactivity of Donor-Acceptor Cyclopropanes: Structural and Electronic Analysis
3) Cycloaddition and Annulation Reactions of Donor-Acceptor Cyclopropanes
4) Activation of Donor-Acceptor Cyclopropanes under Covalent Organocatalysis: Enamine, Iminium, NHC and Phosphine Catalysis
5) Ring-Opening 1,3-Difunctionalization of Donor-Acceptor Cyclopropanes
6) Molecular Rearrangements in Donor-Acceptor Cyclopropanes
7) Donor-Acceptor Cyclopropanes with Amino Group as Donor
8) Chemistry of Cyclopropyl Monocarbonyls
9) Chemistry of Aroyl- and Nitro-substituted Donor-Acceptor Cyclopropanes
10) Metal-free Activation of the Donor-Acceptor Cyclopropanes: Thermal Reactions, Protic Acids and Bases
11) Asymmetric Catalytic Activation of Donor-Acceptor Cyclopropanes
12) Donor-Acceptor Cyclopropanes in Natural Product Synthesis

Erscheinungsdatum
Verlagsort Berlin
Sprache englisch
Maße 170 x 244 mm
Gewicht 960 g
Themenwelt Naturwissenschaften Chemie Organische Chemie
Schlagworte catalysis • Chemie • Chemistry • Cyclopropan • Katalyse • Methods - Synthesis & Techniques • Organische Chemie / Methoden, Synthesen, Verfahren • Organische Synthese • Pharmaceutical & Medicinal Chemistry • Pharmazeutische u. Medizinische Chemie
ISBN-10 3-527-34987-1 / 3527349871
ISBN-13 978-3-527-34987-6 / 9783527349876
Zustand Neuware
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