Stereochemistry

Professor Anil V. Karnik is based at the Department of Chemistry, University of Mumbai, India, where he presently works as a UGC-BSR Fellow (Professor). He has taught stereochemistry and chirality related topics to post-graduate students for more than 30 year, and has delivered hundreds of lectures on various aspects of stereochemistry at different State Universities and colleges in India. His research area includes various fundamental aspects of stereochemistry, which has resulted in quality publications in reputed high impact factor international journals. His research areas include asymmetric organocatalysis, synthesis of sterically crowded biaryl and helical molecules, chiral molecular recognition, kinetic resolutions to name important few. He has also two invited reviews on stereochemistry topics. Dr. Mohammed Hasan has graduated with a PhD in Organic Chemistry form University of Mumbai, working with Prof. Anil V. Karnik on the topic “Studies In Chiral Molecular Recognition”. Post PhD, He began his career as Research Scientist at a pharmaceutical industry, CIPLA Ltd.; working on synthesis of complex, chiral anti-cancer drugs. Later, he went on to gain significant international post-doctoral research experience in Europe and China; working on various synthetic and supramolecular chemistry aspects of stereochemistry. His research interest includes synthetic organic chemistry, chirality, supramolecular chemistry, optical methods and green chemistry. He has many publications in high impact factor international journals. Currently, he is a visiting researcher at the Department of Chemistry, University of Mumbai.

Part I Fundamentals of stereochemistry1. Basic concepts of structure and stereochemistry2. Symmetry and point groups3. Elements of chirality and chiral stereoisomerism

Part II Enantiomer properties4. Chiroptical properties: Origin and applications5. Configurational analysis6. Racemates: Properties and methods of resolution

Part III Conformations and conformational analysis7. Conformation of acyclic molecules8. Conformations of cyclic, fused and bridged ring molecules

Part IV Stereochemical reactivity9. Prochirality10. Diastereomeric transition states and stereoselectivity11. Chiral analytical chemistry12. Pericyclic reactions