Handbook of Proteolytic Enzymes, Two-Volume Set with CD-ROM
Academic Press Inc
978-0-12-079610-6 (ISBN)
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Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more.
Currently Dr. Neil Rawlings is a Senior Scientist in the Proteins Department at the EMBL-European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK. Dr. Rawlings has been an active researcher at the Wellcome Trust Sanger Institute for over twenty years. He is extremely well known in the proteolytic enzyme community for his work curating the MEROPS database, an information resource covering peptidases and the proteins that inhibit them, which is used by expert researchers and students worldwide. Dr. Rawlings has published widely in such peer reviewed journals as Genome Research, BMC Bioinformatics, PloS ONE, Nucleic Acids Research, the Journal of Biological Chemistry, and Science.
Sample of chapters listed according to catalytic type (chapter order will be reorganized by time of publication):
Aspartic Peptidases: Introduction: aspartic peptidases and their clans; Rous sarcoma virus retropepsin and avian myeloblastosis virus retropepsin; Pepsin F
Cysteine Peptidases: Introduction: the clans and families of cysteine peptidases; Coronavirus picornain-like cysteine proteinase; Calicivirus endopeptidases
Metallopeptidases: Introduction: metallopeptidases and their clans; Ophiolysin; Philodryas venom metalloproteinases
Serine Peptidases: Introduction: unsequenced serine peptidases; Muramoyl-pentapeptide carboxypeptidase; Tail-specific protease
Threonine Peptidases: Introduction: clan PB containing N-terminal nucleophile peptidases; HslVU protease; Glycosylasparaginase and other self-processing N-terminal nucleophile amidohydrolases
Unclassified Peptidases: Introduction: peptidases of unknown catalytic type; Murein tetrapeptide LD-carboxypeptidases; Tubulinyl-Tyr carboxypeptidase
| Erscheint lt. Verlag | 27.5.2004 |
|---|---|
| Verlagsort | San Diego |
| Sprache | englisch |
| Gewicht | 7530 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| ISBN-10 | 0-12-079610-4 / 0120796104 |
| ISBN-13 | 978-0-12-079610-6 / 9780120796106 |
| Zustand | Neuware |
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