Molecular Biology of Cancer
Oxford University Press (Verlag)
978-0-19-883302-4 (ISBN)
Using the hallmarks of cancer as a starting point, the book looks at the cellular and molecular mechanisms underpinning the transformation of cells into cancer cells. After discussing the theory, each chapter then demonstrates how this knowledge can be directly applied to the development of new targeted therapies, giving the reader a clear appreciation of how our understanding of the theory can be translated into new approaches for tackling the disease.
The new edition draws on the latest research in cancer biology, highlighting fundamental concepts and re-emphasising pre-existing concepts. The book features a variety of learning features - 'Pause and think', 'How do we know that?', self-tests and activities - to help students engage with, and master, the concepts presented. The emphasis is on acquiring a solid understanding of the essentials and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit.
Molecular Biology of Cancer is supported by online resources and is available for students and institutions to purchase in a variety of formats.
The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks
The online resources include:
For students:
- Multiple choice questions
- Web links to additional cancer biology resources
For registered adopters of the book:
· Figures from the book, available to download
Dr Lauren Pecorino obtained her PhD in Cell and Developmental Biology at the State University of New York at Stony Brook, USA. She then moved to London to carry out a post-doctoral tenure at the Ludwig Institute for Cancer Research where she studied the phenomenon of limb regeneration. Here she used a technique called biolistics, using a 'gene gun' to shoot gold bullets coated with DNA to introduce genes into the regenerating limbs of live newts. Since 1996, Lauren has been a member of academic staff at the University of Greenwich, where she developed her interest in teaching Cancer Biology. In 2018, Lauren was made a Principal Fellow of the Higher Education Academy.
1: Introduction
2: The cancer genome
3: Regulation of gene expression
4: Growth factor signaling and oncogenes
5: The cell cycle
6: Tumor suppressor genes
7: Apoptosis
8: Cancer stem cells and the regulation of self-renewal and differentiation pathways: focus on colon cancer and leukemias
9: Metastasis
10: Angiogenesis
11: Reprogrammed metabolism and diet
12: Tumor immunology and immunotherapy
13: Inflammation, infection, and the microbiome
14: Strategies and tools for research and drug development
| Erscheinungsdatum | 25.06.2021 |
|---|---|
| Verlagsort | Oxford |
| Sprache | englisch |
| Maße | 190 x 247 mm |
| Gewicht | 910 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-19-883302-4 / 0198833024 |
| ISBN-13 | 978-0-19-883302-4 / 9780198833024 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
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