Bioinformatics (eBook)

eBook Download: PDF
2020 | 4. Auflage
656 Seiten
John Wiley & Sons (Verlag)
978-1-119-33596-2 (ISBN)

Lese- und Medienproben

Bioinformatics -
Systemvoraussetzungen
99,99 inkl. MwSt
  • Download sofort lieferbar
  • Zahlungsarten anzeigen
Praise for the third edition of Bioinformatics

"This book is a gem to read and use in practice."
--Briefings in Bioinformatics

"This volume has a distinctive, special value as it offers an unrivalled level of details and unique expert insights from the leading computational biologists, including the very creators of popular bioinformatics tools."
--ChemBioChem

"A valuable survey of this fascinating field. . . I found it to be the most useful book on bioinformatics that I have seen and recommend it very highly."
--American Society for Microbiology News

"This should be on the bookshelf of every molecular biologist."
--The Quarterly Review of Biolog"

The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today's biologists are gaining fantastic new insights into the natural world's most complex systems. These rapidly progressing innovations can, however, be difficult to keep pace with.

The expanded fourth edition of the best-selling Bioinformatics aims to remedy this by providing students and professionals alike with a comprehensive survey of the current field. Revised to reflect recent advances in computational biology, it offers practical instruction on the gathering, analysis, and interpretation of data, as well as explanations of the most powerful algorithms presently used for biological discovery. Bioinformatics, Fourth Edition offers the most readable, up-to-date, and thorough introduction to the field for biologists at all levels, covering both key concepts that have stood the test of time and the new and important developments driving this fast-moving discipline forwards.

This new edition features:

* New chapters on metabolomics, population genetics, metagenomics and microbial community analysis, and translational bioinformatics

* A thorough treatment of statistical methods as applied to biological data

* Special topic boxes and appendices highlighting experimental strategies and advanced concepts

* Annotated reference lists, comprehensive lists of relevant web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics

Bioinformatics is an indispensable companion for researchers, instructors, and students of all levels in molecular biology and computational biology, as well as investigators involved in genomics, clinical research, proteomics, and related fields.

EDITED BY ANDREAS D. BAXEVANIS, PhD, Director of Computational Biology for the National Institutes of Health's Intramural Research Program and a Senior Scientist leading the Computational Genomics Unit at the NIH's National Human Genome Research Institute, Bethesda, MD, USA. GARY D. BADER, PhD, Ontario Research Chair in Biomarkers of Disease and Professor at the Donnelly Centre and the Departments of Molecular Genetics and Computer Science at the University of Toronto, Toronto, ON, Canada. DAVID S. WISHART, PhD, Distinguished University Professor in the Departments of Biological Sciences and Computing Science at the University of Alberta, Edmonton, AB, Canada.

Foreword vii

Preface ix

Contributors xi

About the Companion Website xvii

1 Biological Sequence Databases 1
Andreas D. Baxevanis

2 Information Retrieval from Biological Databases 19
Andreas D. Baxevanis

3 Assessing Pairwise Sequence Similarity: BLAST and FASTA 45
Andreas D. Baxevanis

4 Genome Browsers 79
Tyra G. Wolfsberg

5 Genome Annotation 117
David S. Wishart

6 Predictive Methods Using RNA Sequences 155
Michael F. Sloma, Michael Zuker, and David H. Mathews

7 Predictive Methods Using Protein Sequences 185
Jonas Reeb, Tatyana Goldberg, Yanay Ofran, and Burkhard Rost

8 Multiple Sequence Alignments 227
Fabian Sievers, Geoffrey J. Barton, and Desmond G. Higgins

9 Molecular Evolution and Phylogenetic Analysis 251
Emma J. Griffiths and Fiona S.L. Brinkman

10 Expression Analysis 279
Marieke L. Kuijjer, Joseph N. Paulson, and John Quackenbush

11 Proteomics and Protein Identification by Mass Spectrometry 315
Sadhna Phanse and Andrew Emili

12 Protein Structure Prediction and Analysis 363
David S. Wishart

13 Biological Networks and Pathways 399
Gary D. Bader

14 Metabolomics 437
David S. Wishart

15 Population Genetics 481
Lynn B. Jorde and W. Scott Watkins

16 Metagenomics and Microbial Community Analysis 505
Robert G. Beiko

17 Translational Bioinformatics 537
Sean D. Mooney and Stephen J. Mooney

18 Statistical Methods for Biologists 555
Hunter N.B. Moseley

Appendices 583

Glossary 591

Index 609

Erscheint lt. Verlag 12.2.2020
Sprache englisch
Themenwelt Naturwissenschaften Biologie
Schlagworte Bioinformatics & Computational Biology • Bioinformatik u. Computersimulationen in der Biowissenschaften • Biowissenschaften • Cell & Molecular Biology • Computational Biology • Life Sciences • Mathematics • Mathematik • Mathematik in der Biologie • Zell- u. Molekularbiologie
ISBN-10 1-119-33596-5 / 1119335965
ISBN-13 978-1-119-33596-2 / 9781119335962
Haben Sie eine Frage zum Produkt?
PDFPDF (Adobe DRM)
Größe: 60,0 MB

Kopierschutz: Adobe-DRM
Adobe-DRM ist ein Kopierschutz, der das eBook vor Mißbrauch schützen soll. Dabei wird das eBook bereits beim Download auf Ihre persönliche Adobe-ID autorisiert. Lesen können Sie das eBook dann nur auf den Geräten, welche ebenfalls auf Ihre Adobe-ID registriert sind.
Details zum Adobe-DRM

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seiten­layout eignet sich die PDF besonders für Fach­bücher mit Spalten, Tabellen und Abbild­ungen. Eine PDF kann auf fast allen Geräten ange­zeigt werden, ist aber für kleine Displays (Smart­phone, eReader) nur einge­schränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen eine Adobe-ID und die Software Adobe Digital Editions (kostenlos). Von der Benutzung der OverDrive Media Console raten wir Ihnen ab. Erfahrungsgemäß treten hier gehäuft Probleme mit dem Adobe DRM auf.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen eine Adobe-ID sowie eine kostenlose App.
Geräteliste und zusätzliche Hinweise

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich