Hyperalgesia and Allodynia

Focuses on five topics: nociceptors and their sensitization; the role of nociceptors in primary hyperalgesia; the role of central changes in secondary hyperalgesia; the mechanisms of central changes produced by peripheral nerve damage and the diagnosis, assessment and treatment of hyperalgesia.

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This volume brings together clinical and basic research on primary and secondary hyperalgesia and allodynia, conducted by some of the world's leading neurologists, neurobiologists, neurophysiologists, and pain specialists. Their contributions focus on five key topics; nociceptors and their sensitization; the role of nociceptors in primary hyperalgesia; the role of central changes in secondary hyperalgesia; the mechanisms of central changes produced by peripheral nerve damage; and the diagnosis, assessment, and treatment of hyperalgesia. Subjects discussed include inflammatory and neuropathic hyperalgesic pain, thermal hyperalgesia, cutaneous secondary hyperalgesia, nociceptive processes evoked by acute arthritis, quantitative sensory testing, treatment of hyperalgesia following neural injury, and hyperalgesia and allodynia in patients with central nervous system lesions.