Modern Aryne Chemistry

A. T. Biju received his B. Sc. and M. Sc. from Mahatma Gandhi University, Kerala, India, and Ph.D. under the guidance of Dr. Vijay Nair at the CSIR-NIIST, Trivandrum, India. Subsequently, he has been a post-doctoral fellow with Prof. Tien-Yau Luh at the National Taiwan University, Taipei and an Alexander von Humboldt fellow with Prof. Frank Glorius at the Westf?lische Wilhelms-Universit't M?nster, Germany. In June 2011, he began his independent research career at the CSIR-National Chemical Laboratory, Pune, India. In June 2017, he moved to the Department of Organic Chemistry, IISc Bangalore as associate professor. His research focuses on the development of transition-metal-free carbon-carbon and carbon-heteroatom bond-forming reactions using aryne chemistry and N-heterocyclic carbene (NHC) organocatalysis, and their application in organic synthesis.

Chapter 1. Introduction to the Chemistry of Arynes
Chapter 2. Aryne Cycloadditions for the Synthesis of Functional Polyarenes
Chapter 3. Dipolar Cycloaddition Reactions of Arynes and Related Chemistry
Chapter 4. Recent Insertion Reactions of Aryne Intermediates
Chapter 5. Multicomponent Reactions Involving Arynes and Related Chemistry
Chapter 6. Transition-Metal-Catalyzed Reactions Involving Arynes and Related Chemistry
Chapter 7. Molecular Rearrangements Triggered by Arynes
Chapter 8. New Strategies in Recent Aryne Chemistry
Chapter 9. Hetarynes, Cycloalkynes and Related Intermediates
Chapter 10. Hexadehydro Diels-Alder (HDDA) Route to Arynes and Related Chemistry
Chapter 11. Applications of Benzynes in Natural Product Synthesis