Neuroprotective Natural Products (eBook)

Clinical Aspects and Mode of Action

Goutam Brahmachari (Herausgeber)

eBook Download: PDF
2017
Wiley-VCH Verlag GmbH & Co. KGaA
978-3-527-80379-8 (ISBN)

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Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases.
To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine.
With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.

After receiving his Ph.D. in 1997 at Visva-Bharati University (India), Goutam Brahmachari joined his alma mater and currently holds the position of a full professor of chemistry since 2011. Research interests of his group include green chemistry, organic synthesis and medicinal chemistry of natural products, as well as artificial compounds. With more than 18 years of experience in both teaching and research, he has produced nearly 160 scientific publications including original research papers, review articles, books and invited book chapters in the fields of natural products and green chemistry. He has authored/edited 18 books and more than 30 book chapters so far published by internationally reputed major presses. He is the Series Editor of the Book Series 'Natural Product Drug Discovery'.

Neuroprotective natural products: An overview

Neuroprotective agents: An overview on the general modes of action

Beneficial upshots of naturally occurring antioxidant compounds against neurological disorders

Natural neuroprotectives for the management of Parkinson's Disease

Neuroprotective effect of Ayurvedic preparations and natural products on Parkinson's disease

Lipid peroxidation and mitochondrial dysfunction in Alzheimer's and Parkinson's diseases: Role of natural products as cytoprotective agents

Anti-Alzheimer's agents from sea

Natural products against Huntington's disease: Implications of neurotoxic animal models and trangenics in preclinical studies

Possible role of neuroprotectants and natural products in epilepsy: Clinical aspects and mode of action

Neuroprotective effects of flavonoids in epilepsy

The role of noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors in treatment-resistant depression

Safety and efficacy of Ashwagandha (Withania somnifera)

Cannabinoids: A group of promising neuroprotective agents

Erscheint lt. Verlag 3.3.2017
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Naturwissenschaften Biologie
Naturwissenschaften Chemie
Schlagworte Biowissenschaften • Chemie • Chemistry • Life Sciences • Natural Products • Naturstoffchemie • neuroprotection treatment natural products drugs neurological disorder neurodegeneration flavonoids cannabinoids • Neuroprotektion • Neuroscience • Neurowissenschaften • Pharmaceutical & Medicinal Chemistry • Pharmazeutische u. Medizinische Chemie
ISBN-10 3-527-80379-3 / 3527803793
ISBN-13 978-3-527-80379-8 / 9783527803798
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