Mechanisms in B-Cell Neoplasia 1994

Contains the results of a workshop on intriguing new developments in human B-cell tumour research, covering B-cell biology and the clinical problems posed by multiple myelomas, follicular lymphoma, mantle cell lymphoma and B-CLL.

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The 12th Workshop on Mechanisms in B-Cell Neoplasia continues a series of meetings on intriguing new developments in human and experimental B-cell tumours. The integration of knowledge from basic B-cell biology to the clinical problems of multiple myelomas, follicular lymphoma, mantle cell lymphoma and B-CLL present the challenges that were discussed in the meeting. The discussion focuses on: cellular components of the myeloma clone; genomic instability in B-cells and B-cell tumours; the CD5 antigen and B1 cells; the regulation of cell cycle and apoptosis; and the role of IL-6, BCL-2, BCL-1 and myc in B-cell development.