Acute Lymphoblastic Leukaemia
John Wiley & Sons Inc (Verlag)
978-0-471-56719-6 (ISBN)
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This volume integrates information ranging from molecular biology to the use of bone marrow transplants in the treatment of acute lymphoblastic leukemia (ALL). Focusing on controversial issues, this volume unites basic research and clinical data in evaluating recent progress and pointing out areas for future investigations in leukemia diagnosis and therapy. Timely studies of oncogenes, retroviruses and chromosome alterations provide important data on the mechanistic and developmental aspects of ALL, in addition to exploring the role of hematopoietic growth factors and lymphokines in cell growth regulation. The volume reviews the development of in vitro assays for the analysis of leukemia cells and recent progress in the treatment of adults and children with ALL.
Partial table of contents:; BIOLOGY; Etiology of Childhood Acute Lymphoblastic Leukemia: A Soluble Problem?; (M. Greaves); Some Thoughts on Normal and Leukemic Human B Cell Precursors (T. LeBien); Human B Cell Growth Factors: Current Status and Future Prospects (R. Ford & S. Mehta); CLINICAL STUDIES; Evolving Chromosome Patterns and New Cytogenetic Concepts in Childhood Acute Lymphoblastic Leukemia (D. Williams, et al.); Critical Analysis of Detecting Minimal Residual Leukemia (D. Campana & G. Janossy); Hybrid Leukemias (C. Schiffer); CHEMOTHERAPY; High-Risk Groups Among Children with Acute Lymphocytic Leukemia (G. Rivera, et al.); High-Dose Cytarabine Therapy in Adult Acute Lymphocytic Leukemia (P. Cassileth, et al.); Gimena ALL 0183: A Multicentric Study on Adult Acute Lymphoblastic Leukemia in Italy (F. Mandelli, et al.); TRANSPLANTATION; Bone Marrow Transplantation for ALL in Europe (A. Gratwohl, et al); Bone Marrow Transplantation for Acute Lymphoblastic Leukemia (K. Blume, et al.); Marrow Purging: Are Our Concepts Correct?; (I. Berstein, et al.); CONCLUSION; Controversies in the Biology and Therapy of Acute Lymphoblastic Leukemia (R. Gale & A. Butturini); Acute Lymphoblastic Leukemia: Current Controversies, Future Directions (R. Gale & D. Hoelzer); Index.
| Zusatzinfo | Ill. |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 36 x 58 mm |
| Gewicht | 680 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hämatologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| ISBN-10 | 0-471-56719-1 / 0471567191 |
| ISBN-13 | 978-0-471-56719-6 / 9780471567196 |
| Zustand | Neuware |
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