Chromosomes and Genes in Acute Lymphoblastic Leukemia

Highlighting the changes in the area of acute lymphoblastic leukaemia research, this text reviews both well established methods of banding and the more recent fluorescent "in-situ" hybridization, Southern blotting and polymerase chain reaction techniques.

---

Highlighting the changes that have taken in the area of acute lymphoblastic leukaemia research, this text reviews both well established methods of banding and the newer fluorescent "in-situ" hybridization, Southern blotting and polymerase chain reaction techniques. Important translocations, partial deletions and chromosone gains and losses are illustrated and the clinical and molecular significance of each is described.