Prions and Diseases -

Prions and Diseases

Volume 2, Animals, Humans and the Environment
Buch | Softcover
298 Seiten
2014 | 2013 ed.
Springer-Verlag New York Inc.
978-1-4899-9397-7 (ISBN)
299,59 inkl. MwSt
Volume II covers the etiology, pathogenesis, classification, histopathological and clinical aspects of animal and human prion diseases, including decontamination of prions and development of therapeutics for prion diseases, such as immunomodulation.
Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.

Bovine Spongiform Encephalopathy.- Classical and Atypical Scrapie in Sheep and Goats.- Sporadic Human Prion Disease.- Environmentally-acquired Transmissible Spongiform.- Prions in the Environment.- The Spectrum of Tau Pathology in Human Prion Disease.- Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion.- Species Barriers in Prion Disease.- Transgenic Mice Modelling.- Prion Transmission Studies in Transgenic Mice.- Alternative Models of Prion Diseases.- Diagnosis of Prion Disease: Conventional Approaches.- Quaking-induced Conversion (QuIC) Assays for the Detection and Diagnosis of Prion Diseases.- Overview on Treatment of Prion Diseases and Decontamination of Prions.- Immunomodulation.

Erscheint lt. Verlag 13.12.2014
Zusatzinfo X, 298 p.
Verlagsort New York
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
Schlagworte Bovine spongiform encephalopathy • Chronic wasting disease • Creutzfeldt-Jakob disease • prion diseases • prion protein • Prions • Scrapie
ISBN-10 1-4899-9397-5 / 1489993975
ISBN-13 978-1-4899-9397-7 / 9781489993977
Zustand Neuware
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