Ion Transport Across Membranes (eBook)

Front Cover 1
Ion Transport Across Membranes 4
Copyright Page 5
Table of Contents 12
Contributors 8
Preface 10
Chapter 1. Note on the Work of Jacques Loeb 14
Chapter 2. Ion Transport Across Biological Membranes 16
DIFFUSION THROUGH BIOLOGICAL MEMBRANES 16
ACTIVE TRANSPORT 26
REFERENCES 34
Chapter 3. Electrical Processes in Nerve Conduction 36
PHYSICAL CHARACTERISTICS OF THE RESTING NERVE FIBER 36
VOLTAGE-CURRENT RELATIONS IN THE MEMBRANE 39
THE SEQUENCE OF EVENTS IN A NERVE IMPULSE 42
MYELINATED NERVE FIBERS 43
OVER-ALL CHANGES IN AN IMPULSE 44
GAPS IN THE SCHEME 45
REFERENCES 47
Chapter 4. The Generation of Bioelectric Potentials 48
ACETYLCHOLINESTERASE 52
SEQUENCE OF ENERGY TRANSFORMATIONS 55
THE PROTEINS OP THE ACETYLCHOLINE SYSTEM 61
REFERENCES 76
Chapter 5. Some Optical Observations on the Interaction Between Acetyl Cholinesterase and Its Substrate 78
Chapter 6. Ion Permeability of the Red Cell 82
REFERENCES 87
Chapter 7. Renal Mechanisms of Electrolyte Transport 88
ELECTROLYTE TRANSPORT IN VIVO 89
ELECTROLYTE TRANSPORT IN VITRO 102
REFERENCES 113
Chapter 8. Membrane Permeability and Electrical Potential 116
INTRODUCTION 116
GENERALIZED RELAXATION THEORY 118
MEMBRANE RESTING POTENTIAL 122
TH E NON-STEADY STATE 127
REFERENCES 130
Chapter 9. Transport of Ions Through Biological Membranes From the Standpoint of Irreversible Thermodynamics 132
REFERENCES 140
Chapter 10. Transport of Ions Across Charged Membranes 141
MEMBRANES 141
ELECTRICAL TRANSFERENCE 142
ELECTRICAL POTENTIALS 144
MEMBRANE POTENTIALS 147
BI-IONIC POTENTIALS 150
INTERPRETATION 152
CONCLUSION 155
REFERENCES 155
Chapter 11. Electrochemical Studies with Model Membranes 157
THE FUNDAMENTAL ELECTROCHEMISTRY OF MEMBRANES OF POROUS CHARACTER 157
MEMBRANES OF HIGH ELECTROCHEMICAL ACTIVITY IN PHYSICOCHEMICAL AND MODEL STUDIES OF BIOLOGICAL INTEREST 170
ACKNOWLEDGMENTS 199
REFERENCES 199
Chapter 12. Theory of Protein Solutions 202
INTRODUCTION 202
MCMILLAN-MAYER SOLUTION THEORY 203
DEBYE-HÜCKEL THEORY AND DONNAN EQUILIBRIUM 212
BINDING OF IONS OR MOLECULES ON PROTEIN MOLECULES 219
ACKNOWLEDGEMENTS 232
REFERENCES 233
Chapter 13. Interaction of Proteins and Ions With Special Reference to Mercury Derivatives of Mercaptalbumin 234
ACKNOWLEDGMENTS 257
REFERENCES 257
Chapter 14. The Specificity of Metal-Protein Interactions 259
INTRODUCTION 259
INTERACTIONS WITH REACTIVE GROUPS IN PROTEINS 259
THE SOLUBILITY OF METAL-PROTEIN COMPLEXES 264
ACKNOWLEDGMENT 283
REFERENCES 283
Chapter 15. Equilibrium and Sedimentation of Uncharged Particles in Inhomogeneous Electric Fields 286
GENERAL CONSIDERATIONS AS TO THE ORDER OF MAGNITUDE OF THE EFFECT 286
EXPERIMENTAL ARRANGEMENT USING A CYLINDRICAL CONDENSER 288
NONIDEAL SOLUTIONS 290
DISTURBANCES DUE TO HEATING 292
EFFECT OF ELECTROSTRICTION AND ELECTRIC DOUBLE REFRACTION 294
DEPENDENCE ON TIME 295
FIELD INDUCED DIFFRACTION 297
Author Index 300
Subject Index 306