Epigenetic Regulation of Lymphocyte Development
Springer Berlin (Verlag)
978-3-642-44767-9 (ISBN)
The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
lt;p>Preface.- Roles of lineage-determining transcription factors in establishing open chromatin - lessons from high-throughput studies.- B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.- Epigenetic features that regulate IgH locus recombination and expression.- Local and global epigenetic regulation of V(D)J recombination.- Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.- T-cell identity and epigenetic memory.- Encoding stability versus flexibility: Lessons learned from examining epigenetics in T helper cell differentiation.- The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression.- Subject Index
| Erscheint lt. Verlag | 22.2.2014 |
|---|---|
| Reihe/Serie | Current Topics in Microbiology and Immunology |
| Zusatzinfo | X, 194 p. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 320 g |
| Themenwelt | Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Schlagworte | CD4 co-receptor • CD8 co-receptor • gene expression • IgH locus recombination • recombination activating gene • T-cell identity • T helper cell lineages |
| ISBN-10 | 3-642-44767-8 / 3642447678 |
| ISBN-13 | 978-3-642-44767-9 / 9783642447679 |
| Zustand | Neuware |
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