Vascular Mechanisms in CNS Trauma (eBook)

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2013 | 2014
XX, 518 Seiten
Springer New York (Verlag)
978-1-4614-8690-9 (ISBN)

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Vascular Mechanisms in CNS Trauma -
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While there are a number of books on the market that deal with neuronal mechanisms and targets, the proposed book will be the only one to cover the vascular aspects of CNS trauma. The contributing authors will present basic mechanisms, explain cutting-edge experimental models and techniques, and provide several clinical chapters that provide treating physicians with some insight on the cases that they see in the ICU. The table of contents is diverse and comprehensive with chapters on molecular mechanisms, physiology, pharmacology, stem cells, genomics and proteomics, in vivo MRI and PET, as well as the clinical management of vascular parameters.?
While there are a number of books on the market that deal with neuronal mechanisms and targets, the proposed book will be the only one to cover the vascular aspects of CNS trauma. The contributing authors will present basic mechanisms, explain cutting-edge experimental models and techniques, and provide several clinical chapters that provide treating physicians with some insight on the cases that they see in the ICU. The table of contents is diverse and comprehensive with chapters on molecular mechanisms, physiology, pharmacology, stem cells, genomics and proteomics, in vivo MRI and PET, as well as the clinical management of vascular parameters.

Part I: Molecular Mechanisms 1. CNS Barriers in NeurotraumaAdam Chodobski, Brian J. Zink, and Joanna Szmydynger-Chodobska 2. Mechanisms of Cerebral Edema Leading to Early Seizures after Traumatic Brain InjuryPhilip H. Iffland II, Gerald G. Grant and Damir Janigro 3. Human Cerebral Blood Flow and Traumatic Brain InjuryDavid A. Hovda and Thomas C. Glenn 4. Gliovascular Targets in Traumatic CNS InjuryArjun Khanna, Brian P Walcott, Kristopher T Kahle, Volodymyr Gerzanich, J. Marc Simard 5. Neurovascular Responses to Traumatic Brain InjuryJosephine Lok, Ken Arai, Shu-zhen Guo, Wendy Leung, Takakuni Maki, Deepti Navaratna, Klaus van Leyen, Changhong Xing, and  Eng H. Lo 6. The Effects of Intravascular Coagulation and Microthrombosis on Cerebral Perfusion after Brain Trauma Monisha A. Kumar, Doug H. Smith, and Sherman C. Stein  7. Barriers to Drug Delivery for Brain TraumaRobert S. B. Clark 8. Angiogenesis and Functional Recovery after Traumatic Brain InjuryYanlu Zhang, Ye Xiong, Asim Mahmood, Zheng Gang Zhang, and Michael Chopp  9. Vascular Mechanisms in Spinal Cord InjuryTheo Hagg 10. Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury Kunjan R. Dave, John W. Thompson, Jake T. Neumann, Miguel A. Perez-Pinzon, Hung W. Lin  11. Stem Cells for Neurovascular Repair in CNS TraumaMibel M. Pabón, Travis Dailey, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa, Sandra Acosta, Yuji Kaneko, Cesar V. Borlongan 12. Vascular Actions of Hypothermia in Brain TraumaW. Dalton Dietrich and Helen M. Bramlett Part II: Experimental Models and Methods13. Vascular Responses in Rodent Models of Traumatic Brain InjuryXiaoshu Wang, Zhanyang Yu, Zhengbu Liao, Qi Liu, MingMing Ning, Xiaochuan Sun, Josephine M. Lok, Eng H. Lo, Xiaoying Wang 14. SAH Models: Review, New Modification, and ProspectiveSheng Chen, Damon Klebe, Alexander Vakhmyanin, Mutsumi Fujii, John H. Zhang 15. Age and Sex Differences In Hemodynamics In a Large Animal Model of Brain TraumaWilliam M. Armstead and Monica S. Vavilala 16. Neutrophils as Determinants of Vascular Stability in the Injured Spinal Cord Alpa Mahuvakar, Sang Mi Lee, Haoqian Zhang, and Linda J. Noble-Haeusslein 17. Blood Biomarkers for Acute CNS Insults: Traumatic Brain Injury and StrokeOlena Glushakova, Stefania Mondello, Ronald L. Hayes 18. Biomaterials for CNS Injury Myron Spector and Teck Chuan Lim 19. Isolated Blood Vessel Models for Studying TraumaEugene V. Golanov Part III: Clinical Challenges and Opportunities20. Managing Edema and Intracranial Pressure in the Intensive Care UnitBrian Cummings, Phoebe H. Yager, Sarah A. Murphy, Brian Kalish, Chetan Bhupali, Rebecca Bell, Zenab Mansoor, Natan Noviski, and Michael J. Whalen 21. Surgical Management of Traumatic Brain EdemaTakeshi Maeda, Tatsuro Kawamata, Atsuo Yoshino, Yoichi Katayama 22. Optimizing Hemodynamics in the Clinical SettingJose Alberto Toranzo and Claudia S. Robertson, 23. Cerebrovascular Autoregulation and Monitoring of Cerebrovascular Reactivity Philip M. Lewis, Marek Czosnyka, Piotr Smielewski, John D. Pickard 24. Cerebrovascular Responses after Pediatric Traumatic Brain InjurySteven Shein, Nikki Ferguson, and Michael J. Bell  25. Subdural Hematoma in Non-Accidental Head InjuryJennifer C. Munoz Pareja, Josephine Lok, Natan Noviski, Ann-Christine Duhaime  26. Blood Genomics after Brain Ischemia, Hemorrhage, and TraumaDa Zhi Liu, Glen C Jickling, Boryana Stamova, Xinhua Zhan, Bradley P Ander and Frank R Sharp 27. Molecular Biomarkers in Neurocritical Care – The Next FrontierSherry H-Y Chou and MingMing Ning  28. Bedside Monitoring of Vascular Mechanisms in CNS Trauma: The use of Near Infra-red Spectrpscopy (NIRS) and Transcranial Doppler (TCD)Sarah Murphy, Brian Cummings, David Boas and Natan Noviski 29. In vivo MRI and MRS of Cerebrovascular Function following Traumatic Brain InjuryChandler Sours, Rao P Gullapalli 

Erscheint lt. Verlag 4.11.2013
Reihe/Serie Springer Series in Translational Stroke Research
Springer Series in Translational Stroke Research
Zusatzinfo XX, 518 p. 45 illus., 28 illus. in color.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
Technik
Schlagworte blood-brain barrier • Cerebral Blood Flow • edema • Neuroprotection • spinal cord injury • traumatic brain injury
ISBN-10 1-4614-8690-4 / 1461486904
ISBN-13 978-1-4614-8690-9 / 9781461486909
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