Dendritic Cells in Fundamental and Clinical Immunology

General Introduction: Dendritic cells: Antigen presentation, accessory function and clinical relevance.- Endocytic activity of dendritic cells is similar to other antigen presenting cells.- Immunocytochemical characterization of dendritic cells.- Requirements of exogenous protein antigens for presentation to CD4+ T lymphocytes by MHC Class II-positive APC.- Modulation of MHC Class II determinants on rat Langerhans cells during short term culture.- A dendritic cell specific determinant present in endosomes is involved in the presentation of protein antigens.- Dendritic cells are potent antigen-presenting cells for microbial superantigen.- Divergent T-cell cytokine profiles induced by dendritic cells from different tissues.- Adhesion molecules: Co-stimulators and Co-mitogens in dendritic cell - T cell interaction.- Dendritic cell dependent expression of IgA by clones in T/B microcultures.- Adhesion molecules in tonsil DC-T cell interactions.- Dendritic cells have reduced cell surface membrane glycoproteins including CD43 determinants.- The effect of human dendritic cells on the lectin-induced responsiveness of CD4+ T cells to IL-2 and IL-4.- Analysis of cytokine and cytokine receptor production by human dendritic cells.- Costimulating factors and signals relevant for antigen presenting cell function.- Distinct T cell stimulation mechanism and phenotype of human blood dendritic cells.- The role of dendritic cells in the regulation of T cell cytokine synthesis.- The role of dendritic cells as co-stimulators in tolerance induction.- The influence of dendritic cells on T-cell cytokine production.- Phenotypical and functional characterization of dendritic cells in the human peritoneal cavity.- Dendritic cells isolated from rat and human non-lymphoid tissue are very potent accessory cells.- Antigen presenting capacity of peritoneal macrophages and dendritic cells.- T-cell repertoire development in MHC class II deficient humans.- Rat thymic dendritic cells.- Rat thymic dendriticCells: flow cytometry analysis.- Ultrastructure of interdigitating cells in the rat thymus during Cyclosporin A treatment.- T cell tolerance and antigen presenting cell function in the thymus.- Tolerizing mice to human leukocytes: A step toward the production of monoclonal antibodies specific for human dendritic cells.- Morphological and functional differences between HLA-Dr+ peripheral blood dendritic cells and HLA Dr+ IFN-alpha producing cells.- Three monoclonal antibodies to antigen presenting cells in the rat with differential influence on cellular interactions.- The MHC expression of dendritic cells from mouse spleen isolated by centrifugal elutriation is unregulated during short term culture.- II-6 and its high affinity receptor during differentiation of monocytes into Langerhans cells.- Phagocytosis of antigens by Langerhans cells.- Dissection of human Langerhans cell allostimulatory function. Modulation by interferon-?.- Human in vitro T cell sensitization using hapten-modified epidermal Langerhans cells.- Monocyte-derived Langerhans cells from different species - morphological and functional characterization.- A serial section study of mice Langerhans cell granules after DNFB painting.- Skin dendritic cell-lymphocyte interactions in autologous system.- Induction of the low affinity receptor for IgE (Fc?RII/CD23) on human blood dendritic cells by interleukin-4.- Fc? RI mediates IGE-binding to human epidermal Langerhans cells.- Murine epidermal Langerhans cells as a model to study tissue dendritic cells.- Differentiation of dendritic cells in cultures of ratand mouse bone marrow cells.- TNF and GM-CSF dependent growth of an early progenitor of dendritic Langerhans cells in human bone marrow.- Human bone marrow contains potent stimulatory cells for the allogeneic MLR with the phenotype of dendritic cells.- Recombinant GM-CSF induces in vitro differentiation of dendritic cells from mouse bone marrow.- Signals required for differentiating dendritic cells from human monocytes in vitro.- Down-regulation and release of CD14 on human monocytes by IL-4 depends on the presence of serum or GM-CSF.- Serum-free differentiation of rat and human dendritic cells accompanied by acquisition of the nuclear lamins A/C as differentiation markers.- Immunophenotypic and ultrastructural differentiation and maturation of nonlymphoid dendritic cells in osteopetrotic (op) mice with the total absence of macrophage colony stimulating factor activity.- Loading of dendritic cells with antigen in vitro or in vivo by immunotargeting can replace the need for adjuvant.- Migration of alveolar macrophages from alveolar space to paracortical T cell area of the draining lymph node.- Comparison of Langerhans cells and interdigitating reticulum cells.- Migration of dendritic cells during contact sensitization.- Peritoneal cell labelling: A study on the migration of macrophages and dendritic cells towards the gut.- Dendritic Cells “in vivo”: Migration and antigen handling.- Follicular dendritic cells: Isolation procedures, short and long term cultures.- Heterogeneity and cellular origin of follicular dendritic cells.- Differential uptake and trapping of TI-2 antigens: An unexpected role for follicular dendritic cells in the induction of TI-2 immune responses.- Ultrastructural heterogeneity of follicular dendritic cells in the human tonsil.- Ultrastructuralanalysis of human lymph node follicles after HIV-1 infection.- Emperipolesis of lymphoid cells by human follicular dendritic cells in vitro.- The localization of lymphokines in murine germinal centers.- Two different mechanisms of immune-complex trapping in the mouse spleen during immune responses.- Cellular requirements for functional reconstitution of follicular dendritic cells in SCID mice.- Interaction through the LFA-l/ICAM-1 pathway prevents programmed cell death of germinal center B cells.- Membrane expression of Fc? RII/CD23 and release of soluble CD23 by follicular dendritic cells.- Follicular dendritic cells in malignant lymphomas - Distribution phenotypes & ultrastructures.- Lymphoid follicles in Cynomolgus monkeys after infection with simian immunodeficiency virus.- Destruction of follicular dendritic cells in murine acquired immunodeficiency syndrome (MAIDS).- Changes in follicular dendritic cell and CD8+ cell function in macaque lymph nodes following infection with SIV251.- Rapid and selective isolation of follicular dendritic cells by low speed centrifugations on discontinuous BSA gradients.- Follicular dendritic cells do not produce TNF-? nor its receptor.- Splenic lesions in hypogammaglobulinaemia.- Ontogenic study on the bronchus associated lymphoid tissue (BALT) in the rat, with special reference to dendritic cells.- DRC1 expression on lymphoid normal and pathological cells.- Binding of HIV-1 to human follicular dendritic cells.- Follicular dendritic cells in germinal center reactions.- Follicular dendritic cells and dendritic cell nomenclature.- Langerhans cells as outposts of the dendritic cell system.- Heterogeneity of dendritic cells and nomenclature.- Report of the panel discussion.- Dendritic cells in transplantation.- Down-regulation ofMHC-expression on dendritic cells in rat kidney grafts by PUVA pretreatment.- Cytokine mediators of non-lymphoid dendritic cell migration.- Isolation of dendritic leukocytes from non-lymphoid organs.- RTIB/D+ non-lymphoid DC in early GVHD and Hg-induced autoimmunity of rat salivary and lacrimal glands.- In-vitro infection of peripheral blood dendritic cells with human immunodeficiency virus-1 causes impairment of accessory functions.- Simian immunodeficiency virus (SIV) induced alterations of thymus IDCs.- Murine leukaemia virus infections as models for retroviral disease in humans.- Langerhans cells and interdigitating cells in HIV infection.- Dendritic cells in HIV-1 and HTLV-1 infection.- Dendritic cells in allergic and chronic inflammatory responses.- Pulmonary dendritic cell populations.- Blood dendritic cells are highly adherent to untreated and cytokine-treated cultured endothelium.- Antigen specific T cell priming in vivo by intratracheal injection of antigen presenting cells.- Histology and immunophenotype of dendritic cells in the human lung.- Acquisition of Chlamydial antigen by dendritic cells and monocytes.- Experimental cutaneous leishmaniasis: Langerhans cells internalize Leishmania major and induce an antigen-specific T-cell response.- Endocytosis of potential contact sensitizers by human dendritic cells.- Dendritic cells and “dendritic” macrophages in the uveal tract.- Macrophages and dendritic cells in rat colon in experimental inflammatory bowel disease.- Vaccination with tumor antigen-pulsed dendritic cells induces in vivo resistance to a B cell lymphoma.- Studies on Langerhans cells in the tracheal squamous metaplasia of vitamin A deficient rats.- Depletion of Langerhans cells following carcinogen treatment is partly due to antigenicity.- Aproportion of patients with premature ovarian failure show lowered percentages of blood monocyte derived dendritic cells capable of forming clusters with lymphocytes.- Thyroid hormones and their iodinated breakdown products enhance the capability of monocytes to mature into veiled cells.Blocking effects of ? -GM-CSF.- Relationship between dendritic cells and folliculo-stellate cells in the pituitary: Immuno-histochemical comparison between mouse rat and human pituitaries.- Dendritic cells in tumor growth and endocrine diseases.