Dento/Oro/Craniofacial Anomalies and Genetics (eBook)

Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research. - Comprehensive examination of dento/oro/craniofacial anomalies - Well-illustrated examples - Presented in a compact, easy to use format

A. BLOCH-ZUPAN is a world wide known expert in odontogenetics. Her research interests are craniofacial and specifically palate and tooth development and their abnormalities. Her originality is to combine approaches both in mice and humans presenting these palate and teeth developmental defects as clinical phenotypical manifestations of rare diseases. She is also leading the D[4]/phenodent (see www.phenodent.org) registry for human dental anomalies and a PHRC on Amelogenesis imperfecta.1988 Doctor in Dental Sciences; 1994 PhD, Developmental Biology; 2004 Habilitation à Diriger les Recherches, Louis Pasteur University, Strasbourg; Since 2007 Professor (PU-PH) in Oral Biology, Faculty of Dentistry, University of Strasbourg, France; Reference Centre for Oro-Dental manifestations of rare diseases, Service de Médecine et Soins BuccoDentaires, Hôpitaux Universitaires de Strasbourg; IGBMC Team Leader, Orodental Development and Anomalies llkirch (France). Since 2009 Honorary Professor Eastman Dental Institute, University College London (UCL) and Hospital. Since 2008 Board-Member of the European Society of Human Genetics; Since 2008 President of the scientific committee of the patient support group Hypophosphatasia Europe. 2005-2007 Associate Professor in Oral Biology; 2003-1994 Associate Professor in Paediatric Dentistry; Faculty of Dentistry, University of Strasbourg, France; 2000-2003 Senior Clinical Lecturer in Paediatric Dentistry with Honorary Consultant status, Eastman Dental Institute for Oral Health Care Sciences, University College London (UCL) and Hospital,London, UK; 1998 Institute of Dental Research, Honorary Visiting Dental Officer, Westmead Hospital Dental Clinical School, Australia. 2003-2008 Chairperson and expert of the working group WG3 Genetics/Anomalies of the European COST (European Concerted Research Action B23) 'Oral facial development and regeneration”.

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Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research. - Comprehensive examination of dento/oro/craniofacial anomalies- Well-illustrated examples- Presented in a compact, easy to use format