Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids

I. Epidemiology and Ecology of Bacterial Plasmids.- Evolution Among Antibiotic Resistance Plasmids in the Hospital Environment.- R Factors Present in Epidemic Strains on Shigella and Salmonella Species Found in Mexico.- Trimethoprim-Resistant Bacteria in Hospital and in the Community: Spread of Plasmids and Transposons.- Ecological Factors That Affect the Survival, Establishment, Growth and Genetic Recombination of Microbes in Natural Habitats.- Epidemiology and Genetics of Hemolysin Formation in Escherichia Coli.- Dorothee Miiller and Colin Hughes Chromosomal and Plasmid-Mediated Transfer of Clindamycin Resistance in Bacteroides Fragilis.- Campylobacter Jejuni: Characteristic Features of the Organism and Identification of Transmissible Plasmids in Tetracycline-Resistant Clinical Isolates.- Studies on Drug Resistance Transposons in HaemophilusInfluenzae R Plasmids.- Plasmids in Streptococci: A Review.- II. Pathogenicity: Mechanisms and contributing Factors.- Bacterial Pathogenicity, An Overview.- Cloning and Expression of the Genes Encoding for the Adhesive Antigens K88 and K99.- Invasive Bacterial Pathogens of the Intestine: Shigella Virulence Plasmids and Potential Vaccine Approaches.- Plasmid-Specified Iron Uptake by Bacteraemic Strains of Escherichia Coli.- Serum Resistance in E. Coli.- III. Mechanisms of Resistance.- Antibiotic Resistance — A Survey.- Regulation of Plasmid Specified MLS-Resistance in Bacillus Subtilis by Conformational Alteration of RNA Structure.- Control and DNA Structure of the ampC ?-Lactamase Gene of Escherichia Coli.- Mechanisms of Plasmid-Determined Heavy Metal Resistances.- IV. Transfer and Mobilization of Plasmids.- Conjugation and Resistance Transfer in Streptococci and Other Gram Positive Species: Plasmids, Sex Pheromones andConjugative Transposons (A Review).- Sites and Systems for Conjugal DNA Transfer in Bacteria.- Conjugative Pili of Plasmids in Escherichia Coli K-12 and Pseudomonas Species.- The Pathway of Plasmid Transformation in Pneumococcus.- Plasmids of the Gonococcus.- Genetic Organization and Expression of Non-Conjugative Plasmids.- V. Plasmid Replication, Maintenance and Incompatibility.- Structure-Function Relationships in Essential Regions for Plasmid Replication.- Control of Plasmid Replication and Its Relationship to Incompatibility.- Structure and Function of the Replication Origin Region of the Resistance Factors R100 and Rl.- Plasmid Rl Incompatibility. Contribution From the cop/rep and From the par Systems.- Copy Number Control and Incompatibility of incFII R Plasmids.- Replication and Incompatibility Functions in Mini-F Plasmids.- Plasmid Mini-F Encoded Functions Involved in Replication and Incompatibility.- Nucleotide Sequence Change in a ColEl Copy Number Mutant.- VI. Transposition and Genetic Rearrangements.- Transposition and Rearrangements in Plasmid Evolution.- Complementation of Transposition Functions Encoded by Transposons Tn501(HgR) and Tnl721(TetR).- The Structure of Tn5.- Transposition of the Inverted Repeats of Tn15.- Host Functions Required for Transposition of Tn5 from ?b221 c1857 rex: :Tn5.- Plasmid Mobilization As A Tool for In Vivo Genetic E1ngineering.- VII. Medical, Public Health and Industrial Applications of Plasmids.- Proinsulin From Bacteria.- Construction and Properties of Plasmid Vectors Containing the trp Regulatory Region Suitable for Expressing Foreign Genes.- Isolation and Analysis of a Cosmid Hybrid Containing the Human Genomic Interferon Gene, HuIFN?l.- Development of Broad Host-Range Plasmid Vectors.- The Survival of EK1 and EK2Systems in Sewage Treatment Plant Models.- cos Plasmid in Bacillus Subtilis.- A Mutational and Transcriptional Analysis of a Tumor Inducing Plasmid of Agrobacterium Tumefaciens.- Transfer, Maintenance and Expression of Genes Introduced into Plant Cells Via the Tl Plasmid.- Rhizobium Plasmids: Their Role in the Nodulation of Legumes.- Metabolic Plasmid Organization and Distribution.- Degradative Plasmids: TOL and Beyond.- Plasmids in the Biodegradation of Chlorinated Aromatic Compounds.- VIII. Effects of Antibiotic Usage on Antibiotic Resistance in Man and Animals.- Antibiotic Resistance of Gram Negative Bacteria in Mexico: Relationship to Drug Consumption.- Plasmid Mediated Ampicillin Resistance in a Strain of Haemophilus Pleuropneumoniae Isolated from Swine.- R Plasmids in Pathogenic Enterobacteriaceae from Calves.- Effects of Antibiotics in Animal Feed on the Antibiotic Resistance of the Gram Positive Bacterial Flora of Animals and Man.- Multiply-resistant Clones of Salmonella Typhimurium in Britian: Epidemiological and laboratory aspects.- IX. Brief Reports on all Topics.- Statement Regarding Worldwide Antibiotic Misuse.- Conference Participants.- Author Index.