Growth Hormone Secretagogues

I. Overview: Historical Perspective.- Growth Hormone Releasing Factor: A Brief History of Its Time.- 2. Xenobiotic Growth Hormone Secretagogues: Growth Hormone Releasing Peptides.- II. Chemistry of Growth Hormone Secretagogues.- 3. Synthetic Analogues of Growth Hormone Releasing Factor (GHRF) with Improved Pharmaceutical Properties.- 4. Structure, Function, and Regulation of the Pituitary Receptor for Growth Hormone Releasing Hormone.- 5. Computer-Assisted Modeling of Xenobiotic Growth Hormone Secretagogues.- 6. Growth Hormone Releasing Peptides.- 7. Nonpeptidyl Growth Hormone Secretagogues.- 8. A Weak Substance P Antagonist Inhibits L-692,585-Stimulated GH Release in Swine.- 9. Growth Hormone Releasing Hormone Receptor in Human Breast Cancer Cell Line MCF-7.- III. Cellular and Molecular Properties of Growth Hormone Secretagogues.- 10. Cellular Physiology of Growth Hormone Releasing Hormone.- 11. Mechanism of Action of GHRP-6 and Nonpeptidyl Growth Hormone Secretagogues.- 12. Metabolic Regulation of Growth Hormone Secretagogue Gene Expression.- IV. Physiology of Growth Hormone Secretagogues.- 13. The Role of Growth Hormone Releasing Hormone (GHRH) and Growth Hormone (GH) in the Onset of Puberty and During Glucocorticoid-Altered Growth.- 14. Clinical Studies with Growth Hormone Releasing Hormone.- 15. Central and Peripheral Effects of Peptide and Nonpeptide GH Secretagogues on GH Release In Vivo.- 16. Evidence for a Central Site and Mechanism of Action of Growth Hormone Releasing Peptide (GHRP-6).- 17. Animal Models for Evaluating Xenobiotic Growth Hormone Secretagogue Activity.- 18. A Diagnostic Test Employing Growth Hormone Secretagogues for Evaluating Pituitary Function in the Elderly.- V. Target Tissues and Applications for Growth Hormone Secretagogues.- 19. Transdifferentiation of Growth Hormone and Prolactin Secreting Cells.- 20. Growth Hormone Releasing Hormone: Behavioral Evidence for Direct Central Actions.- 21. Growth Hormone (GH) Releasing Hormone- and Thyrotropin Releasing Hormone-Induced GH Release in the Acute Phase of Trauma.- 22. Effects of Hexarelin on Growth Hormone Secretion in Short Normal Children, in Obese Children, and in Subjects with Growth Hormone Deficiency.- 23. Lymphocytes and Hypothalamic Peptides.- 24. Growth Hormone Releasing Peptide—Hexarelin—in Children: Biochemical and Growth Promoting Effects.- 25. Growth Hormone Secretagogues in Disease States Associated with Altered Growth Hormone Secretion.- 26. Growth Hormone Releasing Hormone (GHRH) Effects in Healthy Aging Men.- 27. Aging and Growth Hormone Releasing Peptides.- 28. Growth Hormone Relationships to Immune Function in Humans.- Author Index.