The Influence of Antibiotics on the Host-Parasite Relationship II

Herr Professor Helmut Hahn ist emeritiert und im Vorstand der Berliner Medizinischen Gesellschaft aktiv.

I. The Influence of Antibiotics on the Morphology and the Surface of Bacteria.- Effect of Subinhibitory Concentrations of Antibiotics on Surface Proteins of Neisseria gonorrhoeae and Neisseria meningitidis: Changes that Alter Attachment of Human Cells.- Interaction of Aminoglycosides and Ciprofloxacin with Bacterial Membranes.- The Influence of Ciprofloxacin on the Ultrastructure of Gram-negative and Gram-positive Bacteria.- Exposure of Protein Antigens and Reduction of Siderophore Production after growth of Gram-Negative Bacteria in Sub-Inhibitory Concentrations of Cephalosporins.- The Influence of ß-Lactam Antibiotics Including Monobactam on the outer and inner Membrane of E. coli.- Changes in outer Membrane Composition after Treatment of Proteus mirabilis with Antibiotics.- Weight and Morphology of Bacteria Exposed to Antibiotics.- II. The Influence of Antibiotics on Immunogenicity.- Immunogenicity of Bacteria Treated in vitro with Subinhibitory Concentrations of Antibiotics.- Influence of Subminimal Inhibitory Concentrations of Antibiotics on Antigen Expression and Metabolic Activity of Salmonella Species.- Influence of Ciprofloxacin on Specific Interactions on Listeria-specific T Cells with Antigen in vitro.- III. The Influence of Antibiotics on the Interaction of Bacteria with Host Defence Mechanisms.- a) Serum Bactericidal Activity.- Effects of Antibiotics on the Sensitivity of Proteus mirabilis to the Bactericidal Action of Normal Human Serum.- Imipenem Renders Serum Resistant Enterobacter aerogenes and Escherichia coli to Serum Sensitive Bacteria.- b) Phagocytosis.- Influence of Subinhibitory Concentrations of Clindamycin on the Phagocytosis of Staphylococcus aureus.- The Effect of Antibiotics on the Killing of E. Coli by Macrophages of the Cell Line P 388D1.- Antibiotics and Polyelectrolytes Modulate Bacteriolysis and the Capacity of Bacteria to Trigger an Oxygen Burst in Neutrophils.- Chemiluminescence of Macrophages induced by Non-Opsonized E. coli treated with Subinhibitory Concentrations of ?-Lactam Antibiotics.- Indirect Antibiotic Effects on Granulocyte Migration and Phagocytosis.- Interactions between human Polymorphonuclear Neutrophils and Ampicillin treated Escherichia coli.- The Effect of Subinhibitory Concentrations of selected Antibiotics on Bacteria-Phagocyte Interactions.- The effect of subinhibitory concentrations of monobactams and bactericidal activity of macrophages.- IV. The Influence of Antibiotics on the Pathogenicity Factors and Virulence.- a) Adherence.- Effects of Antibiotics on Streptococcal Adherence: Release of Fibronectin-Lipoteichoic Acid Complexes from Group A Streptococci by Sublethal Concentrations of Penicillin.- Influence of Subinhibitory Concentrations of Antibiotics on Aggregation and Adherence of Streptococcus mutans.- b) Toxin Production and Virulence.- Clostridium Difficile Colonization of Infant Hamsters.- Gentamicin and Tobramycin selectively inhibit the secretion of Pseudomonas aeruginosa elastase.- Subinhibitory concentrations of antibiotics modulate amount of Shiga-like toxin produced by Escherichia coli.- Interference of ciprofloxacin with the expression of pathogenicity factors of Pseudomonas aeruginosa.- V. Miscellaneous.- In vivo Consequences of the Interaction between Antibiotic-damaged Pathogens and Host Animal Defences.- The Influence of Streptomycin on the Ecology of the Intestine and Resistance to Infection.- Protection of tracheal explants infected with Pseudomonas aeruginosa by subinhibitory concentrations of aminoglycosides.- Use of Lectins to CharacterizeSurface Alternations of ?-Lactam Resistant mutants of Pseudomonas aeruginosa.