Transport Processes in Eukaryotic and Prokaryotic Organisms (eBook)
934 Seiten
Elsevier Science (Verlag)
978-0-08-054321-5 (ISBN)
This book presents a state of the art review on the analysis of a wide variety of transport systems from bacteria and eukaryotic cells. A selection has been made of those systems that have been studied at the molecular level with special emphasis paid to the energetic and other biophysical properties. The different classes of transport systems are presented in the following: primary transport, secondary transport, phosphotransferase systems, channels and porines and macromolecular transport. Within each class of transporters several systems are presented by the leading experts in the field, which has resulted in a very broad overview of transport processes in biological cells. In this way the differences in the mechanisms used for translocation become evident while on the other hand features common to the different transport systems are revealed.
In recent years it has become evident that transport processes across membranes play a crucial role in many metabolic systems. The activities of these transport processes often determine the physiology of the organisms.This book presents a state of the art review on the analysis of a wide variety of transport systems from bacteria and eukaryotic cells. A selection has been made of those systems that have been studied at the molecular level with special emphasis paid to the energetic and other biophysical properties. The different classes of transport systems are presented in the following: primary transport, secondary transport, phosphotransferase systems, channels and porines and macromolecular transport. Within each class of transporters several systems are presented by the leading experts in the field, which has resulted in a very broad overview of transport processes in biological cells. In this way the differences in the mechanisms used for translocation become evident while on the other hand features common to the different transport systems are revealed.
Cover 1
Contents of Volume 2 12
General Preface 6
Preface 10
Contributors 16
Part 1: Primary Transport 22
Ion pumps 22
Chapter 1. ATP–coupled Pumps for Heavy Metals and Metalloids 22
Chapter 2. Sodium lon Coupled F1F0 ATPases 42
Chapter 3. F-Type H + ATPase (ATP Synthase): Catalytic Site and Energy Coupling 68
Chapter 4. The Neurospora Plasma Membrane Proton Pump 96
Chapter 5. Structure and Function of the Yeast Vacuolar Membrane H+-ATPase 114
Multidrug resistance and export systems 132
Chapter 6. Structure and Function of HlyB, the ABC-transporter Essential for Haemolysin Secretion from Escherichia coli 132
Chapter 7. The P-Glycoprotein Family and Multidrug Resistance: An Overview 158
Chapter 8. Multidrug Resistance in Prokaryotes: Molecular Mechanisms of Drug Efflux 186
Part 2: Secondary Transport 210
Substrate transport and exchangers 210
Chapter 9. Molecular Genetic Analysis of Membrane Protein Topology 210
Chapter 10. The Lactose Permease of Escherichia coli: Past, Present and Future 224
Chapter 11. Secondary Transporters and Metabolic Energy Generation in Bacteria 250
Chapter 12. Pi-Linked Anion Exchange in Bacteria: Biochemical and Molecular Studies of UhpT and Related Porters 282
Chapter 13. Structure of the Erythrocyte Band 3 Anion Exchanger 302
Chapter 14. Erythrocyte Sugar Transport 332
Chapter 15. The Mediator of Thyroidal Iodide Accumulation: The Sodium/Iodide Symporter 364
Chapter 16. The Vertebrate Na+/H + Exchangers: Structure, Expression and Hormonal Regulation 390
Neurotransmitters 402
Chapter 17. Biogenic Amine Transporters of the Plasma Membrane 402
Chapter 18. From Multidrug Resistance to Vesicular Neurotransmitter Transport 426
Chapter 19. Structure and Function of Sodium–Coupled Amino Acid Neurotransmitter Transporters 402
Homeostasis 468
Chapter 20. lntracellular pH: Measurement, Manipulation and Physiological Regulation 468
Chapter 21. K + Circulation Across the Prokaryotic Cell Membrane: K+-uptake Systems 494
Chapter 22. Bacterial Na+/H + Antiporters - Molecular Biology, Biochemistry and Physiology 522
Part 3: Phosphotransferase Systems 554
Chapter 23. Biophysical Aspects of Carbohydrate Transport Regulation in Bacteria 554
Chapter 24. Domain and Subunit Interactions and Their Role in the Function of the E. coli mannitol transporter, Eli MTL 570
Chapter 25. Phosphotransferase Systems or PTSs as Carbohydrate Transport and as Signal Transduction Systems 594
Part 4: Channels and Porines 620
Chapter 26. lon Selectivity and Substrate Specificity: The Structural Basis of Porin Function 620
Chapter 27. Intrinsic and Extrinsic Channels in Bacteria 636
Chapter 28. Communication Between Membranes in TonB-Dependent Transport Across the Bacterial Outer Membrane 658
Chapter 29. Colicin Transport, Channel Formation and Inhibition 686
Chapter 30. Bacterial Ion Channels 714
Part 5: Macromolecule Transport 752
Chapter 31. Transport of DNA Through Bacterial Membranes 752
Chapter 32. Translocation of Proteins Across the Bacterial Cytoplasmic Membrane 780
Chapter 33. Protein Transport Across the Outer and Inner Membranes of Mitochondria 812
Author lndex 844
Subject Index 944
| Erscheint lt. Verlag | 11.9.1996 |
|---|---|
| Sprache | englisch |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik | |
| Technik | |
| ISBN-10 | 0-08-054321-9 / 0080543219 |
| ISBN-13 | 978-0-08-054321-5 / 9780080543215 |
| Haben Sie eine Frage zum Produkt? |
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