Systems Biology and Biotechnology of Escherichia coli (eBook)

Sang Yup Lee (Herausgeber)

eBook Download: PDF
2009 | 2009
XXI, 462 Seiten
Springer Netherland (Verlag)
978-1-4020-9394-4 (ISBN)

Lese- und Medienproben

Systems Biology and Biotechnology of Escherichia coli -
Systemvoraussetzungen
213,99 inkl. MwSt
  • Download sofort lieferbar
  • Zahlungsarten anzeigen

Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.


Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.

1 Biological Features and Biotechnological Applications of Escherichia coli B: 'Is B for better?!'; 2 Escherichia coli Genome Engineering and Minimization for the Construction of a Bioengine; 3 Multi-omics Data-driven Systems Biology of E. coli; 4 A Medium-Throughput Structural Proteomics Approach Applied to the Genome of E. coli; 5 Resources for Escherichia coli Systems Biology; 6 The Multiple Scientific Disciplines Served by EcoCyc; 7 Analysis of E. coli Network; 8 Sensory Transduction Network of E. coli; 9 Genome-Scale Reconstruction, Modeling, and Simulation of E. coli’s Metabolic Network; 10 Kinetic Modeling of E.coli Enzymes: Integration of in vitro Experimental Data; 11 Dynamic Modeling of the Central Metabolism of E. coli – Linking Metabolite and Regulatory Networks; 12 Genome-scale Models and the Genetic Basis for E. coli Adaptation; 13 Organisation of Complex Escherichia coli Promoters; 14 Plasmid Regulation and Systems-Level Effects on Escherichia coli Metabolism; 15 Systems-level analysis of protein quality in inclusion body-forming Escherichia coli cells; 16 Mechanistic Challenges and Engineering Applications of Protein Export in E. coli; 17 Engineering E. coli Central Metabolism for Enhanced Primary Metabolite Production; 18 Glucose and Acetate Metabolism in E. coli - System Level Analysis and Biotechnological Applications in Protein Production Processes; 19 Performance Characteristics for Sensors and Circuits Used to Program E.coli; 20 Systems Metabolic Engineering of E. coli; Index

Erscheint lt. Verlag 20.3.2009
Zusatzinfo XXI, 462 p.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Technik Umwelttechnik / Biotechnologie
Schlagworte A complete resource for anyone interested in systems biology • Biology • Biotechnology • Design • Expression • Glucose • Metabolism • Proteomics
ISBN-10 1-4020-9394-2 / 1402093942
ISBN-13 978-1-4020-9394-4 / 9781402093944
Haben Sie eine Frage zum Produkt?
PDFPDF (Wasserzeichen)
Größe: 27,6 MB

DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasser­zeichen und ist damit für Sie persona­lisiert. Bei einer missbräuch­lichen Weiter­gabe des eBooks an Dritte ist eine Rück­ver­folgung an die Quelle möglich.

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seiten­layout eignet sich die PDF besonders für Fach­bücher mit Spalten, Tabellen und Abbild­ungen. Eine PDF kann auf fast allen Geräten ange­zeigt werden, ist aber für kleine Displays (Smart­phone, eReader) nur einge­schränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich
Das Lehrbuch für das Medizinstudium

von Florian Horn

eBook Download (2020)
Georg Thieme Verlag KG
69,99
Das Lehrbuch für das Medizinstudium

von Florian Horn

eBook Download (2020)
Georg Thieme Verlag KG
69,99