Myasthenia Gravis and Myasthenic Disorders

Dr. Andrew Engel is the McKnight-3M Professor of Neuroscience and Professor of Neurology, Mayo Clinic College of Medicine as well as the Director of the Neuromuscular Disease laboratory at the Mayo Clinic, Rochester, MN campus. He earned his medical degree at McGill University, was trained in Neurology at the NIH and the Mayo Clinic and in Neuropathology at Columbia University and has spent his entire professional carrier at the Mayo Clinic. Dr Engel has had a longstanding interest in neuromuscular diseases and especially those affecting neuromuscular transmission.

Chapter 1: The Anatomy and Molecular Architecture of the Neuromuscular, Andrew G. Engel, MD ; Chapter 2: Electrodiagnosis of Myasthenic Disorders, C. Michel Harper, MD ; Chapter 3: The Immunopathogenesis of Myasthenia Gravis, Reinhard Hohlfeld, Hartmut Wekerle, and Alexander Marx ; Chapter 4: Natural History of Myasthenia Gravis, Vladimir Luchanok, MD, PhD, and Henry J. Kaminski, MD ; Chapter 5: The Diagnosis of Myasthenia Gravis and Other Disorders of Neuromuscular Transmission, James F. Howard, JR., M.D. ; Chapter 6: Therapy of Myasthenia Gravis, Daniel B. Drachman, M.D. ; Chapter 7: The Lambert-Eaton Myasthenic Syndrome, Vern C. Juel, M.D., and Donald B. Sanders, M.D. ; Chapter 8: Congenital Myasthenic Syndromes, Andrew G. Engel, M.D., Xin-Ming Shen, Ph.D., Kinji Ohno, M.D., Ph.D, Steven M. Sine, Ph.D. ; Chapter 9: End-Plate Acetylcholine Receptor, a Target for Myasthenic Disorders: Structural and Mechanistic Essentials, Steven M. Sine and Andrew G. Engel ; Chapter 10: Peripheral Nerve Hyperexcitability Syndromes, Srikanth Muppidi, M.D. and Steven Vernino, M.D., Ph.D. ; Chapter 11: Effects of Antiganglioside Antibodies at the Neuromuscular Junction, Jaap J. Plomp and Hugh J. Willison