Xenotransplantation

1 Molecular and Cellular Hurdles to Xenotransplantation.- 2 Pathological Responses to Xenotransplantation.- 3 Natural Xenoreactive Antibodies.- 4 Specificity of Xenoreactive Natural Antibodies.- 5 Biophysical Properties of Xenoreactive Natural Antibodies.- 6 The Origin of Xenoreactive Natural Antibodies.- 7 Synthesis of Carbohydrate Antigens Recognized by Xenoreactive Antibodies.- 8 The Complement Barrier to Xenotransplantation.- 9 Defects and Amplification of Costimulation Across the Species.- 10 Antibody-Dependent Effects on Cellular Immunity.- 11 Disordered Regulation of Coagulation and Platelet Activation in Xenotransplantation.- 12 Current Applications of Cellular Xenografts.

"This book provides a useful and concise review of the current status of xenotransplantion and introduces the reader to the remaining required developments before effective implementation of xenotransplantation can occur...The editor and authors are recognized authorities in the field of xenotransplantation and this book is an important addition to existing literature on this topic" - Doody's Health Sciences Book Review Journal