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Modern Fluoroorganic Chemistry – Synthesis, Reactivity, Applications

P Kirsch (Autor)

Software / Digital Media
320 Seiten
2005
Wiley-VCH Verlag GmbH (Hersteller)
978-3-527-60393-0 (ISBN)
179,95 inkl. MwSt
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For synthetic chemists who want to understand the implications of including the highly unusual element fluorine in organic compounds, this book presents a range of synthetic methodologies. The experimental procedures selected show that this can be done with standard laboratory equipment also. It also looks at fluorous chemistry.
In this handbook, Peer Kirsch clearly shows that this exciting field is no longer an exotic area of research. Aimed primarily at synthetic chemists wanting to gain a deeper understanding of the fascinating implications of including the highly unusual element fluorine in organic compounds, the main part of the book presents a wide range of synthetic methodologies, and the experimental procedures selected undeniably show that this can be done with standard laboratory equipment. To round off, the author looks at fluorous chemistry, and the applications of organofluorine compounds in liquid crystals, polymers and more besides. This long-awaited book represents an indispensable source of high quality information for everyone working in the field.

Peer Kirsch received his PhD under the supervision of Prof. Staab at the Max Planck Insitute for Medical Research in Heidelberg. He joined the Liquid Crystal Division of Merck KGaA in 1995 and his research interest is the application of fluorine chemistry for the design and synthesis of liquid crystals.

INTRODUCTION Why Organofluorine Chemistry History The Basic Materials The Unique Properties of Organofluorine Compounds SYNTHESIS OF COMPLEX ORGANOFLUORINE COMPOUNDS Introduction of Fluorine Perfluoroalkylation Special Fluorinated Groups Syntheses with Fluorinated Building Blocks FLUOROUS CHEMISTRY Fluorous Biphasic Catalysis Fluorous Synthesis and Combinatorial Chemistry FLUOROPHARMACEUTICALS Why Fluorinated Pharmaceuticals? Lipophilicity Hydrogen bonding and Electrostatic Interactions Metabolic Stabilization Bioisosteric Mimicking Orthogonal Reactivity and Suicide Inhibition LIQUID CRYSTALS FOR ACTIVE MATRIX LCDs Calamatic Liquid Crystals: A Short Introduction Functioning of an Active Matrix LCD Why Fluorinated Liquid Crystals? Fluorinated Polar Groups Fluorinated Bridge Structures REFERENCES

Erscheint lt. Verlag 4.7.2005
Verlagsort Weinheim
Sprache englisch
Gewicht 10 g
Themenwelt Naturwissenschaften Chemie Organische Chemie
ISBN-10 3-527-60393-X / 352760393X
ISBN-13 978-3-527-60393-0 / 9783527603930
Zustand Neuware
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