Bioinformatics – From Genomes to Drugs

Thomas Lengauer (born 1952) studied Mathematics and Informatics at Berlin and Stanford. After a brief stay at the Bell Laboratories, he held various academic positions at the universities of Saarbruecken, Paderborn, and Bonn. From 1992 to 2001, he headed the Institute for Algorithms and Scientific Computing at the GBM in Sankt Augustin (Germany). Since 2001, he is director at the Max Planck Institute for Informatics in Saarbruecken (Germany). Professor Lengauer has recently been awarded the Konrad Zuse Medal, the highest honor of the German Informatics Society.

VOLUME I From Genomes to Drugs with Bioinformatics An Overview Sequence Analysis Structure, Properties and Computer Identification of Eukaryotic Genes Analyzing Regulatory Regions in Genomes Homology Modeling in Biology and Medicine Protein Structure Prediction Protein Ligand Docking in Drug Design Modelling Protein Protein and Protein DNA Docking Glossary VOLUME II Integrating and Accessing Molecular Biology Resources Bioinformatics Support of Genome Sequencing Projects Analysis of Sequence Variations Proteome Analysis Target Finding in Genomes and Proteomes Screening of Drug Databases Future Trends