Organocopper Reagents in Organic Synthesis

Norbert Krause received his PhD from the Technical University of Braunschweig, Germany in 1986. After postdoctoral stays at the ETH Zurich and Yale University, he joined TU Darmstadt where he obtained his lecturing qualification in 1993. The following year he moved to the University of Bonn as an associate professor, before taking up his present position as a full professor at Dortmund University of Technology in 1998. He has been a fellow of the Japan Society for the Promotion of Science, a guest professor at the Universite Catholique de Louvain, Belgium, the University of California, Santa Barbara, USA, and at the Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris, France. Professor Krause has been on the editorial board of the European Journal of Organic Chemistry between 2006 and 2013. His research focuses on the stereoselective synthesis and transformation of functionalized allenes, taking advantage of coinage metal catalysis.

INTRODUCTION Preparation of Organocopper Reagents Mechanism of Organocopper Reactions MICHAEL--ADDITION REACTIONS Additions to Enones Additions to Enolates Additions to Acetylenic Esters and Ketones Additions to other unsaturated Acceptors Additions to Dienones and Dienoates Additions to Acceptor Substituted Enynes Other additions CARBOCUPRATIONS REACTIONS Carbocupration of Alkynes Carbocupration of other Unsaturated Substrates SUBSTITUTION REACTIONS Substitution of Saturated Electrophiles Substitution of Propargylic Electrophiles SN"-- Substitutions