High-Yield™ Biochemistry

Preface

Acknowledgments



1 Acid-Base Relationships

I.Acidic dissociation
II.Measures of acidity
III.Buffers
IV.Acid-base balance
V.Acid-base disorders
VI.Clinical relevance: diabetic ketoacidosis

2 Amino Acids and Proteins

I.Functions of proteins
II.Proteins as polypeptides
III.Protein structure
IV.Protein solubility and R-groups
V.Protein denaturation
VI.Clinical relevance

3 Enzymes

I.Energy relationships
II. Free-energy change
III.Enzymes as biological catalysts
IV. Michaelis-Menten equation
V. Lineweaver-Burk equation
VI.Enzyme
regulation
VII.Clinical relevance: methanol and ethylene glycol poisoning

4 Citric Acid Cycle and Oxidative Phosphorylation

I.Cellular energy and adenosine triphosphate
II.Citric acid cycle
III.Products of the citric acid cycle (one revolution)
IV.Synthetic function of the citric acid cycle
V.Regulation of the citric acid cycle
VI.Electron transport and oxidative phosphorylation
VII.Chemiosmotic hypothesis
VIII.Clinical relevance

5 Carbohydrate Metabolism

I.Carbohydrate digestion and absorption
II.Glycogen metabolism
III. Glycolysis
IV.Gluconeogenesis
V.Regulation of glycolysis and gluconeogenesis
VI.Pentose phosphate pathway
VII.Sucrose and lactose metaboli sm
VIII.Clinical relevance

6 Lipid Metabolism

I.Lipid function
II.Lipid digestion
III.Lipoprotein transport and metabolism
IV.Oxidation of fatty acids
V.Fatty acid synthesis
VI.Glycerolipid synthesis
VII.Sphingolipid synthesis
VIII.Cholesterol synthesis
IX. Clinical relevance

7 Amino Acid Metabolism

I. Functions of amino acids
II.Removal of amino acid nitrogen
III.Urea cycle and detoxification of NH+
IV.Carbon skeletons of amino acids
V.Clinical relevance: inherited (inborn) errors of amino acid metabolism

8 Nucleotide Metabolism

I.Nucleotide structure
II.Nucleotide function
III. Purine nucleotide synthesis
IV.Pyrimidine nucleotide synthesis
V.Deoxyribonucleotide synthesis
VI.Nucleotide degradation
VII.Clinical relevance

9 Nutrition

I.Energy needs
II.Macronutrients
III.Micronutrients: the fat-soluble vitamins
IV.Micronutrients: the water-soluble vitamins
V.Minerals

10 Gene Expression

I.Genetic information
II.DNA and RNA: nucleic acid structure
III.DNA synthesis (replication)
IV.Transcription
V.Translation (protein synthesis)
VI.Mutations

11 Biochemical Technology

I.Protein purification
II.Protein analysis
III.DNA analysis
IV.Cloning of recombinant DNA and protein
V.Clinical relevance

12 Hormones

I.Overview
II.Classification of hormones
III.Mechanisms of hormone action
IV.Hormones that regulate fuel metabolism
V.Hormones that regulate salt and water balance
VI.Hormones that regulate calcium and phosphate metabolism
VII.Hormones that regulate body size and metabolism
VIII.Hormones that regulate the male reproductive system

abbreviated Table of Contents"