Primary Immunodeficiency Diseases

Definition, Diagnosis, and Management
Buch | Softcover
XXVIII, 358 Seiten
2008 | 2008
Springer Berlin (Verlag)
978-3-540-78537-8 (ISBN)

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This highly practical book describes the definition, etiology, clinical manifestations, diagnosis and management of all PID. It also provides guidelines for diagnosis and treatment of patients, which are useful in clinical practice and health planning alike.
Primary immunodeficiency diseases (PID) are a group of disorders involving defects in one or more components of the immune system, and are characterized by an increased incidence of infections, autoimmunity, and malignancies. Although PID seem to be rare, the number of patients diagnosed has increased in recent years, and more than 150 different forms of PID have been identified. Nevertheless, because of inadequate medical awareness, a significant number of patients with PID are either not recognized as having a PID or are not diagnosed as early as they should be. Such delays lead to a substantial increase in morbidity and mortality among affected individuals.
Our understanding of PID is improving rapidly, which will hopefully lead to more accurate diagnosis and efficient disease management. This book contains the most recent advances in the field, as well as a concise and structured review of previously identified PID. Although the book's primary focus is on practical diagnosis and management, the pathophysiology of PID is also discussed.
This book is a comprehensive yet manageable resource for physicians and nurses wishing to learn more about PID, as well as a useful tool for both doctors-in-training and specialists in clinical decision-making and treatment planning.

An Introduction to Primary Immunodeficiency Diseases.- Combined T and B Cell Immunodeficiencies.- Predominantly Antibody Deficiencies.- Phagocytes Defects.- Genetic Disorders of Immune Regulation.- Defects in Innate Immunity: Receptors and Signaling Components.- Autoinflammatory Disorders.- Complement Deficiencies.- Other Well-Defined Immunodeficiencies.- Syndromic Immunodeficiencies.- Treatment of Primary Immunodeficiency Diseases.

From the reviews:

"This is a great book. ... The book is written by a number of well recognised authors who are experts in their field and there is international representation. ... The chapters are well-written and up-to-date. ... The book is punctuated throughout with very good colour clinical photographs that help bring out some of the salient points in the text, and are to be recommended. ... an excellent book and there should be at least one copy in every immunology department, university and hospital library." (Andrew Gennery, Immunology News, May, 2009)

"It provides a useful and easy-to-read update, covering most of the disorders associated with defects in lymphocytes, phagocytes, and complement. ... This will be informative for health planners. ... Clinicians ... will inevitably follow the many citations at the end of each chapter. ... immunologists and specialist nurses managing the care of patients with primary immunodeficiency diseases should have this text on their shelves, as should general pediatric departments and hospital medical libraries. The book will likewise be of interest to scientists ... ." (A. D. B. Webster, Journal of the American Medical Association, Vol. 302 (9), September, 2009)

Erscheint lt. Verlag 12.8.2008
Zusatzinfo XXVIII, 358 p.
Verlagsort Berlin
Sprache englisch
Maße 203 x 276 mm
Gewicht 1005 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete
Schlagworte autoimmunity • Cell • Clinical Manifestations • Definition • Diagnosis • Diseases • etiology • immune system • immunity • Immunodeficiency • Immunologie • Infection • Infections • Innate Immunity • Management • pathophysiology • Physiology • Primary immunodeficiency diseases
ISBN-10 3-540-78537-X / 354078537X
ISBN-13 978-3-540-78537-8 / 9783540785378
Zustand Neuware
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