Functional Metabolism – Regulation and Adaptation

Ken Storey?is a Professor in the Institute of Biochemistry at Carleton University and holds the Canada Research Chair in Molecular Physiology. His research focuses on the molecular adaptations that permit animals to survive severe environmental stresses and his work has explored the many intriguing ways that animals alter their metabolism, modify enzyme function, and regulate gene expression to endure deep cold, oxygen deprivation and water restriction, or meet the multiple demands of muscle exercise metabolism. The author of over 450 research publications and the editor of 5 other books, Dr. Storey has lectured on biochemical adaptation on every continent and has done research in places as diverse as the Amazon jungle and the Antarctic ice shelf. He has received multiple fellowships and awards and is an elected fellow of the Royal Society of Canada and of the American Association for the Advancement of Science.

Preface. Contributors. Chapter 1: Principles of Metabolic Control (William C. Plaxton). Chapter 2: Enzymes: The Basis of Catalysis (Stephen P.J. Brooks). Chapter 3: Enzymes in the Cell: What's Really Going On? (Stephen P.J. Brooks). Chapter 4: Signal Transduction Pathways and the Control of Cellular Responses to External Stimuli (Justin A. MacDonald). Chapter 5: Tyrosine Phosphorylation and the Control of Cellular Information (Justin A. MacDonald). Chapter 6: Control of Transcription in Eukaryotic Cells (William G. Willmore). Chapter 7: Translational Controls and Protein Synthesis in Eukaryotic Cells (William G. Willmore). Chapter 8: The Mitochondria: Powerhouse of the Cell (Kyra J. Cowan). Chapter 9: Human Energy Metabolism in Health and Disease (Steven C. Greenway). Chapter 10: Hormones in Human Metabolism and Disease (Steven C. Greenway) Chapter 11: Skeletal Muscle Metabolism and Plasticity (Denis R. Joanisse). Chapter 12: Oxygen in Biology and Biochemistry: Role of Free Radicals (Marcelo Hermes--Lima). Chapter 13: Oxidative Stress and Medical Sciences (Marcelo Hermes--Lima). Chapter 14: Biochemical Adaptation (Kenneth B. Storey). Chapter 15: Oxygen Limitation and Metabolic Rate Depression (Kenneth B. Storey and Janet M. Storey). Chapter 16: Mammalian Hibernation: Biochemical Adaptation and Gene Expression (Kenneth B. Storey and Janet M. Storey). Chapter 17: Cold Hardiness and Freeze Tolerance (Janet M. Storey and Kenneth B. Storey). Chapter 18: Aspects of Blood Cell Biochemistry: Erythrocytes, Platelets, and Stem Cells (Jean E. Grundy). Chapter 19: Organ Preservation for Transplantation (Thomas A. Churchill). Chapter 20: Metabolic Evolution and the Origin of Life (Tolga Bilgen).