Human Polygenic Diseases

Complex genetic factors are difficult to study in humans. This text aims to provide a concise view of the major experimental models of polygenic inheritance of predisposition to diseases. It emphasizes the use of models as tools for understanding the basis of the complex genetics of human disease.

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This volume deals with the emerging role of complex genetic factors in the pathogenesis of common diseases. These diseases include hypertension, diabetes, obesity, and cancer, and cause a large fraction of morbidity and death. Complex genetic factors are difficult to study in humans, and this book will give the reader a concises view of the major experimental models of polygenic inheritance of predisposition to diseases. It emphasizes the use of models as tools for understanding the basis of the complex genetics of human diseases. This publication can be used as both a reference tool and as a textbook for specialized university courses. it should be of interest to those involved in basic research in animal genetics. molecular genetics, human genetics, and medicine.