Handbook of Experimental Pharmacology / Targeted Drug Delivery
Seiten
1991
Springer Berlin (Hersteller)
978-3-540-52843-2 (ISBN)
Springer Berlin (Hersteller)
978-3-540-52843-2 (ISBN)
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Considers the the biological basis of drug targeting and the use of protein engineering and molecular biological approaches.
Pharmacological research has been initiating new ways of administering drugs that seem like magic. New delivery systems are leaving the beaten paths of oral administration and injections and are instead forging alternative routes that are more direct and cause less damage to body sites visited along the way. "Targeted Drug Delivery" considers the biological basis of drug targeting and the use of protein engineering and molecular biological approaches. Ten chapters review topics at the forefront of research: polymeric systems, microparticulate systems, transdermal delivery and the use of prodrugs in delivery. This text may be of interest to clinicians as well as researchers, focusing on developments in controlled and targeted drug delivery. This handbook on pharmacology, pharmaceutics, biochemistry, polymer science, oncology and chemotherapy is intended for clinicians and researchers.
Pharmacological research has been initiating new ways of administering drugs that seem like magic. New delivery systems are leaving the beaten paths of oral administration and injections and are instead forging alternative routes that are more direct and cause less damage to body sites visited along the way. "Targeted Drug Delivery" considers the biological basis of drug targeting and the use of protein engineering and molecular biological approaches. Ten chapters review topics at the forefront of research: polymeric systems, microparticulate systems, transdermal delivery and the use of prodrugs in delivery. This text may be of interest to clinicians as well as researchers, focusing on developments in controlled and targeted drug delivery. This handbook on pharmacology, pharmaceutics, biochemistry, polymer science, oncology and chemotherapy is intended for clinicians and researchers.
A new perspective for drug delivery research; internalization and sorting of macromolecules; transport of macromolecule across the capillary endothelium; pharmacokinetics in drug targeting: specific implications to targeting via prodrugs; engineering proteins and peptides for drug delivery; soluble polymers as targetable drug carriers; systemic delivery of pharmacologically active molecules across the skin; chemical delivery systems; antisense oligonucleotides as pharmacological modulators of gene expression; in vivo behaviour of liposomes; interactions with the RES and implications for drug targeting.
| Reihe/Serie | Handbook of Experimental Pharmacology ; Vol.100 |
|---|---|
| Zusatzinfo | 112 figs., 24 tabs. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Gewicht | 770 g |
| Einbandart | gebunden |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Schlagworte | Arzneitherapie • Arzneitherapie / Arzneibehandlung • Pharmakologie |
| ISBN-10 | 3-540-52843-1 / 3540528431 |
| ISBN-13 | 978-3-540-52843-2 / 9783540528432 |
| Zustand | Neuware |
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