Basic Immunology

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California

Chapter 1: Introduction to the Immune System The Nomenclature, General Properties, and Components of the Immune System Chapter 2: Innate Immunity The Early Defense Against Infections Chapter 3: Antigen Capture and Presentation to Lymphocytes What Lymphocytes See Chapter 4: Antigen Recognition in the Adaptive Immune System Structure of Lymphocyte Antigen Receptors and the Development of Immune Repertoires Chapter 5: Cell-Mediated Immune Responses Activation of T Lymphocytes by Cell-Associated Microbes Chapter 6: Effector Mechanisms of Cell-Mediated Immunity Eradication of Intracellular Microbes Chapter 7: Humoral Immune Responses Activation of B Lymphocytes and Production of Antibodies Chapter 8: Effector Mechanisms of Humoral Immunity The Elimination of Extracellular Microbes and Toxins Chapter 9: Immunologic Tolerance and Autoimmunity Self-Nonself Discrimination in the Immune System and Its Failure Chapter 10: Immune Responses Against Tumors and Transplants Immunity to Noninfectious Transformed and Foreign Cells Chapter 11: Hypersensitivity Diseases Disorders Caused by Immune Responses Chapter 12: Congenital and Acquired Immunodeficiencies Diseases Caused by Defective Immune Responses Suggested Readings Appendix I: Principal Features of CD Molecules Appendix II: Glossary Appendix III: Clinical Cases Index