Challenging Cases in Gynecologic Surgical Pathology

Ozlen Saglam, MD

Oregon Health and Science University

Department of Pathology and Laboratory Medicine

Portland, OR

USA

Section 1: The Ovarian and Fallopian Tube Pathology Cases.- Chapter 1: Epithelial Ovarian Lesions.- Case Title  1: Endometrioid Carcinoma with Spindle Cells (ECSC).- Case Title  2: Endometrioid Adenocarcinoma with Sertoliform Pattern.- Case Title  3: Low-grade Serous Carcinoma (LGSC) in the background of Serous Borderline Tumor (SBT).- Case Title  4: Lymph Node Involvement by Serous Borderline Tumor.- Case Title  5: High-grade Serous Carcinoma with Solid Endometrioid-like and Transitional (SET) Pattern.- Case Title  6: High-grade Serous Carcinoma with Treatment Effect.- Case Title  7: High-grade Serous Carcinoma with microcytic pattern (mucinous differentiation).- Case Title  8: Mucinous Borderline Tumor with Intraepithelial (non-invasive) Carcinoma (MBT with IECA).- Case Title  9: Serous Borderline Tumor (SBT) with Extraovarian Disease (Implants).- Case Title  10: Borderline Brenner Tumor with Mucinous Metaplasia.- Chapter2: Fallopian Tube Lesions.- Case Title  11: Papillary Tubal Hyperplasia (PTH).- Case Title  12: High-grade Serous Carcinoma in the Background of Serous Tubal Intraepithelial Carcinoma (STIC).- Case Title  13: Mucinous Metaplasia of Bilateral Fallopian Tubes in Peutz-Jeghers Syndrome (PJS).- Chapter 3: Sex Cord Stromal Tumors of the Ovaries and its Mimickers.- Case Title  14: Cellular Fibroma (CF).- Case Title  15: Cystic Adult Granulosa Cell Tumor (AGCT).- Case Title  16: Sertoli Leydig Cell Tumor (SLCT) with Heterologous Elements.- Case Title  17: Juvenile Granulosa Cell Tumor (JGCT).- Case Title  18: Adult Granulosa Cell Tumor (AGCT) with prominent fibromatous component (diffuse pattern).- Case Title  19: Luteinized Adult Granulosa Cell Tumor.- Case Title  20: Stromal Hyperplasia and Hyperthecosis.- Case Title  21: Leydig Cell Tumor (LCT).- Case Title  22: Steroid Cell Tumor (SCT).- Case Title  23: Microcytic Stromal Tumor (MST).- Case Title  24: Gynandroblastoma.- Case Title  25: Sertoli Leydig Cell Tumor with retiform pattern.- Chapter 4: Germ Cell Tumors.- Case Title  26: Well-differentiated Neuroendocrine Tumor (WNET) in the background Mature Teratoma.- Case Title  27: Immature teratoma with embryoid bodies (Malignant Mixed Germ Cell Tumor).- Case Title  28:  Struma Ovarii.- Chapter 5: Miscellaneous Ovarian Lesions.- Case Title  29: Small Cell Carcinoma of the ovary, hypercalcemic type (SCCOHT).- Case Title  30: Anastomosing Hemangioma.- Section 2: Uterine Corpus Pathology Cases.- Chapter 6: Endometrium.- Case Title  1: Corded and Hyalinized Endometrioid Carcinoma (CHEC).- Case Title  2: Metastatic Carcinoma Involving the Endometrium.- Case Title  3: Endometrioid Carcinoma with Mucinous Features.- Case Title  4: Low-grade Endometrioid Adenocarcinoma with Clear Cells.- Case Title  5: Low-grade Endometrioid Adenocarcinoma with Papillary Architecture.- Case Title  6: Endometrioid Carcinoma with Microcystic Elongated and Fragmented (MELF) Pattern of Myometrial Invasion.- Case Title  7: Endometrioid Adenocarcinoma with Progestin Treatment Effect.- Case Title  8: Endometrial Mucinous Metaplasia with Complex Architecture.- Case Title  9: Polypoid Adenomyoma (PAM).- Case Title  10: Atypical Polypoid Adenomyoma (APA).- Case Title  11: Mesonephric-like Adenocarcinoma.- Case Title  12: Undifferentiated/dedifferentiated carcinoma.- Case Title  13: Clear Cell Carcinoma, oxyphilic type.- Case Title  14: Mixed Neuroendocrine and Endometrioid Carcinoma.- Case Title  15: Yolk Sac Tumor of the Endometrium.- Chapter 7: Mesenchymal Lesions.- Case Title  16: Leiomyoma with hydropic change.- Case Title  17: Epithelioid Leiomyoma.- Case Title  18: Intravenous Leiomyomatosis (IVL).- Case Title  19: Disseminated Peritoneal Leiomyomatosis (DPL).- Case Title  20:  Cotyledonoid Dissecting Leiomyoma (CDLM).- Case Title  21: Fumarate Hydratase Deficient Leiomyoma (FH-leiomyoma).- Case Title  22: Leiomyomas with bizarre nuclei (Symplastic leiomyoma).- Case Title  23: Epithelioid Leiomyosarcoma (ELMS).- Case Title  24: Cellular Leiomyoma.- Case Title  25: Perivascular Epithelioid Cell Neoplasm (PEComa).- Case Title  26: Solitary Fibrous Tumor (SFT).- Case Title  27: Myxoid Leiomyosarcoma (LMS).- Case Title  28: Mullerian Adenosarcoma (MA) with Stromal Overgrowth.- Chapter 8: Miscellaneous Uterine Lesions.- Case Title  29: Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT).- Section 3: Uterine Cervix Pathology Cases.- Chapter 9: Uncommon Tumors and mimickers of cancer.- Case Title  1: Mesonephric Hyperplasia (MH).- Case Title  2: Endocervicosis.- Case Title  3: HPV-associated invasive endocervical adenocarcinoma (EAC) with SilvaPattern A.- Case Title  4: Gastric-type Adenocarcinoma (HPV-independent adenocarcinoma) (GAS).- Case Title  5: Neurotrophic tyrosine receptor kinase (NTRK)-rearranged spindle cell neoplasm.- Case Title 6: Epithelioid Trophoblastic Tumor (ETT).- Case Title 7: Residual endocervical adenocarcinoma with treatment effect.- Case Title 8: Small Cell Neuroendocrine Carcinoma of the Cervix (SCNEC).- Case Title 9: Stratified Mucin-Producing Intraepithelial Lesion (SMILE).- Case Title 10: Embryonal Rhabdomyosarcoma (ERMS), botryoid type.- Section 4: Vulvar Pathology Cases.- Chapter 10:  Uncommon Tumors and mimickers of cancer.- Case Title 1: Nodular Hyperplasia (NH) of Bartholin Glands (BG).- Case Title 2: Hidradenoma Papilliferum (Papillary hidradenoma) (HP).- Case Title 3: Molluscum Contagiosum.- Case Title 4: Fibroepithelial polyp (FEP) with giant stromal cells.- Case Title 5: Hibernoma.- Case Title 6: Cellular Angiofibroma (CA).- Case Title 7: Schwannoma with Intralesional Nodularity.- Case Title 8: Extramammary Paget's disease with underlying adenocarcinoma.- Case Title 9: Basal Cell Carcinoma (BCC) of the Vulva, Nodular/Adenoid subtype.- Case Title 10: Differentiated Vulvar Intraepithelial Neoplasia (dVIN) (HPV- independent VIN).- Case Title 11: Deep (Aggressive) Angiomyxoma (AA).- Case Title 12: Pseudovascular Squamous Cell Carcinoma.- Pseudoangiosarcomatous Carcinoma). - Case Title 13: Epithelioid hemangioendothelioma (EHE).