T Cell Metabolism and Cancer Immunotherapy

Dr. Song is Professor of Microbial Pathogenies and Immunology at Texas A&M University Health Science Center, Bryan, TX Is highly motivated to pursue an academic research career in Microbial Pathogenesis and Immunology. The base of expertise on T cell biology needed to perform the proposed research began to develop while he was a postdoctoral scholar and research scientist from the years 2000-2007 under the mentorship of Dr. Michael Croft at La Jolla Institute for Allergy & Immunology. As a PI on previous university-, foundation- and NIH-funded grants, he laid the groundwork for the proposed research by developing antigen-specific T lymphocytes from pluripotent stem cells.. He offered leadership and administrative skills that were developed during his independence as a mentor of graduate students and postdoctoral scholars.

1. Modulating T cell metabolism to improve T cell therapy
2. Links between the DNA damage response and immune response in cancer
3. Improving adoptive T cell therapy by positive conversion of negative signaling
4. TGF-β in tumor microenvironment, metabolism, and immunotherapy
5. Targeting Immunometabolism to Improve Cancer Therapies
6. TCR-T Cells for Cancer Immunotherapy
7. The Combination of Local Treatment and Immunotherapy
8. T cell metabolism and cancer immunotherapy
9. Exploring the Interplay of Kinases and Transcription Factors in Immunometabolism
10. Targeting Engineered Bacteria to Improve Cancer Immunotherapy
11. Salmonella: A Bacterial Warrior in Cancer Immunotherapy
12. Oncolytic Virus for Cancer Immunotherapy
13. Advances in Immunotherapy for Colorectal Cancer