Perioperative Transfusion Medicine

INTRODUCTION

A History of Transfusion

The Contemporary Economics of Transfusion

Blood Supplies Now and in the Future

Medical Ethics, Transfusion and the Standard of Practice

THE PHYSIOLOGIC BASIS FOR BLOOD MANAGEMENT: A NEW LOOK

Oxygen Transport Monitoring: The Basis for Developing Transfusion Triggers

The Physiology of Anemia and Red Blood Cell Transfusion

Physiology of Hemostasis

Platelet Physiology: Cellular and Protein Interactions

Iron Metabolism and Erythopoiesis

New Concepts of Oxygen Transport

TRANSFUSION RISKS

Infectious Risks of Transfusion

Immunomodulation by Transfusion

Serious Acute Transfusion Reactions

BLOOD COMPONENT THERAPY

A Surgeon's Guide to Blood Banking and Transfusion Medicine

Blood Storage

Platelets

Quality Control and Hospital Blood Utilization

ALTERNATIVES TO ALLOGENEIC BLOOD

Preoperative Autologous Donation

Erythropoetin Therapy

Hemoglobin Based Oxygen Carriers

Perfluorocarbon Emulsions

TRAUMA AND THE BLEEDING PATIENT

Initial Resuscitation of the Hemorrhaging Patient

Transfusion and Coagulation Therapy in Trauma and Burns

Acute Gastrointestinal Bleeding and Transfusion Management

Coagulation in Trauma: Dilution and Massive Transfusion

COAGULATION ISSUES

Coagulation Product Use in the Perioperative Period

Coagulation Monitoring in the Perioperative Period

Perioperative Management of Patients with Congenital and Acquired Clotting Deficiencies

Management of Patients with Congenital Clotting Deficiencies Who Require Surgery

Perioperative Management of the Hypercoagulable Patient

Pharmacological Approaches to Prevent or Decrease Bleeding in Surgical Patients

Fibrin Glue and Platelet Gels

ANESTHESIA CONSIDERATIONS

Anesthesia Techniques in Blood Conservation

Perioperative Red Cell Salvage and Autotransfusion

Intraoperative Acute Nomovolemic Hemodilution

Hypothermia and Hemorrhage

TRANSFUSION AND SURGICAL SUBSPECIALTIES

Surgery in Patients with Red Cell Disorders: Sickle Hemoglobinopathies, Polycythemia, and Autoimmune Hemolytic Anemia

Surgery in the Jehovah's Witness

Coagulation and Transfusion Therapy in Cardiac Surgery

Blood Loss and Transfusion Alternatives in Vascular Surgery

Solid Organ Transplantation

Blood Use in Orthopedic Surgery

TRANSFUSION ISSUES IN OTHER SPECIALTIES

Blood Management in Obstetrics and Gynecology

Hemorrhage in Pediatric Patients

Transfusion in Oncologic Surgery

POST-OPERATIVE TRANSFUSION ISSUES

Transfusion and Outcome

The Transfusion Decision

Undertransfusion

A Philosophy of Blood Management