The Challenge of Tuberculosis in the 21st Century

Alberto L. García-Basteiro is Associate Research Professor at the Barcelona Institute for Global Health (ISGlobal) – Hospital Clínic in Barcelona (Spain) and coordinates the TB research area at the Centro de Investigação em Saúde de Manhiça (CISM) in Manhica (Mozambique). Füsun Öner Eyüboğlu currently practices at her private clinic and holds adjunct teaching positions at private medical schools. Molebogeng X. Rangaka is a Professor in Infectious Disease Epidemiology and Public Health at the Institute of Global Health and the MRC Clinical Trials Unit, University College London (London, UK). She holds the position of honorary Associate Professor at the University of Cape Town (Cape Town, South Africa).

International efforts to reverse and end the tuberculosis pandemic: past, present and future global strategies; Epidemiology: the current burden of tuberculosis and its determinants; Host–pathogen interactions in the context of tuberculosis infection and disease; Clinical presentation of pulmonary and extrapulmonary tuberculosis; Microbiological tests and laboratory tests: the value of point-of-care testing; The evolution of imaging and portable imaging tools to aid tuberculosis diagnosis; The differential diagnosis of thoracic tuberculosis: a guide to under- and over-diagnosis; The basis of tuberculosis treatment: fundamental concepts before treating a patient; Treatment of drug-susceptible and drug-resistant tuberculosis; Diagnosis of tuberculosis infection; Preventive therapies for tuberculosis infection; How close are we to a new, effective tuberculosis vaccine? Recent advances in the field; Genomic approaches to tuberculosis management and control; The challenge of post-tuberculosis lung disease; Tuberculosis in children and adolescents: a forgotten group in a forgotten disease; Protecting the most vulnerable: tuberculosis in immunocompromised individuals; Tuberculosis in prisons: a growing global health concern; How do migrations affect tuberculosis burden? Tuberculosis control among migrant populations; Preparedness for successful TB control: lessons from the COVID-19 pandemic; Epilogue: A view of tuberculosis care from tuberculosis survivors