Testosterone -

Testosterone

Action, Deficiency, Substitution

E. Nieschlag, H. M. Behre (Herausgeber)

Buch | Hardcover
762 Seiten
2004 | 3rd Revised edition
Cambridge University Press (Verlag)
978-0-521-83380-6 (ISBN)
155,85 inkl. MwSt
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This is an authoritative, reference on testosterone, and its role in human physiology and pathology. It covers biosynthesis, mechanisms of action and reviews effects on brain and behaviour, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and lipids, erection, and the prostate. Therapeutic and contraceptive applications are assessed.
This book provides information on testosterone and other androgens, and their role in human physiology and pathology. It covers biosynthesis and mechanisms of action and reviews their effects on brain and behaviour, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and lipids, erection, and the prostate. Therapeutic uses of testosterone preparations are carefully evaluated, including use in women, the aging male, and its abuse and detection in sport. The book reviews applications in male contraception, the role of 5a-reductase inhibitors and the controversial use of DHEA. For this book the editors have assembled the world leaders in testosterone research and clinical andrology and endocrinology. A special feature of the book is the fact that its 24 chapters were submitted simultaneously to insure rapid publication. This revised and significantly expanded edition will serve as the standard source of reference for many years.

Preface; 1. Testosterone: an overview of biosynthesis, transport, metabolism and non-genomic actions F. F. G. Rommerts; 2. The androgen receptor: molecular biology H. Klocker, J. Gromoll and A. C. B. Cato; 3. Androgen receptor: pathophysiology O. Hiort and M. Zitzmann; 4. Behavioural correlates of testosterone K. Christiansen; 5. The role of testosterone in spermatogenesis G. F. Weinbauer, M. Niehaus and E. Nieschlag; 6. Androgens and hair: a biological paradox V. A. Randall; 7. Androgens and bone metabolism M. Zitzmann and E. Nieschlag; 8. Testosterone effects on the skeletal muscle S. Bhasin, T. W. Storer, A. B. Singh, L. Woodhouse, R. Singh, J. Artaza, W. E. Taylor, I. Sinha-Hikim, R. Jasuja and N. Gonzalez-Cadavid; 9. Androgens and erythropoiesis M. Zitzmann and E. Nieschlag; 10. Testosterone and cardiovascular diseases A. von Eckardstein and F. C. W. Wu; 11. Testosterone and erection H. M. Behre; 12. Testosterone and the prostate J. T. Isaacs; 13. Clinical use of testosterone in hypogonadism and other conditions E. Nieschlag and H. M. Behre; 14. Pharmacology of testosterone preparations H. M. Behre, C. Wang, D. J. Handelsman and E. Nieschlag; 15. Androgen therapy in non-gonadal disease P. Y. Liu and D. J. Handelsman; 16. Androgens in male senescence J. M. Kaufman, G. T'Sjoen and A. Vermeulen; 17. The pathobiology of androgens in women N. Burger and P. Casson; 18. Clinical use of 5a-reductase inhibitors K. D. Kaufman; 19. Dehydroepiandrosterone (DHEA) and androstenedione B. Allolio and W. Arlt; 20. Selective androgen receptor modulators (SARMs) S. S. Wolf and M. Obendorf; 21. Methodology for measuring testosterone, DHT and SHBG in a clinical setting M. Simoni; 22. Synthesis and pharmacological profiling of new orally active steroidal androgens A. Grootenhuis, M. de Gooyer, J. van der Louw, R. Bursi and D. Leysen; 23. Hormonal male contraception: the essential role of testosterone E. Nieschlag, A. Kamischke and H. M. Behre; 24. Abuse of androgens and detection of illegal use W. Schänzer; Index.

Erscheint lt. Verlag 1.4.2004
Mitarbeit Assistent: S. Nieschlag
Zusatzinfo 22 Tables, unspecified; 2 Halftones, unspecified; 120 Line drawings, unspecified
Verlagsort Cambridge
Sprache englisch
Maße 180 x 254 mm
Gewicht 1652 g
Themenwelt Studium 1. Studienabschnitt (Vorklinik) Physiologie
ISBN-10 0-521-83380-9 / 0521833809
ISBN-13 978-0-521-83380-6 / 9780521833806
Zustand Neuware
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