Hematology

Part I. Molecular and Cellular Basis of Hematology Chapter 1Anatomy and Physiology of the Gene Chapter 2Genomic Approaches to the Study of Hematologic Science NEW Chapter 3Protein Synthesis, Processing, and Degradation REORGANIZED Chapter 4Protein Architecture: Relationship of Form and Function Chapter 5Regulation of Cellular Response NEW Chapter 6Cell Adhesion Chapter 7Control of Cell Division Chapter 8Cell Death NEW Chapter 9Consequences of Genetic Diversity to Hematologic Disease and Treatment NEW Part II. Immunologic Basis of Hematology Chapter 10B-Cell Development Chapter 11T-Cell and NK-Cell Immunity REORGANIZED Chapter 12Dendritic Cell Biology NEW Chapter 13Regulation of Lymphocyte Activation Chapter 14Lymphocyte Trafficking NEW Chapter 15Tolerance and Autoimmunity Part III. Biology of Stem Cells and Disorders of Hematopoiesis Chapter 16Stem Cell Model of Hematopoiesis Chapter 17Anatomy and Physiology of Hematopoiesis Chapter 18Humeral Regulation of Hematopoiesis NEW Chapter 19Biology of Erythroppoiesis, Erythroid Differentiation, and Maturation Chapter 20Granulopoiesis and Monocytopoiesis Chapter 21Thrombocytopoiesis Chapter 22Defects in Platelet Production NEW Chapter 23Inherited Forms of Bone Marrow Failure Chapter 24Aplastic Anemia Chapter 25Paroxysmal Nocturnal Hemoglobinuria Chapter 26Pure Red Cell Aplasia Part IV. Red Blood Cells Chapter 27Pathobiology of the Human Erythrocyte and Its Hemoglobins Chapter 28Approach to the Adult and Child with Anemia Chapter 29Anemia of Chronic Diseases Chapter 30Disorders of Iron Metabolism: Iron Deficiency and Overload Chapter 31Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias Chapter 32Megablastic Anemias Chapter 33Thalassemia Syndromes Chapter 34Pathology of Sickle Cell Disease Chapter 35Clinical Manifestations and Treatment of Sickle Cell Disease NEW Chapter 36Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias Chapter 37Red Cell Enzymopathies Chapter 38Red Cell Membrane Disorders Chapter 39Autoimmune Hemolytic Anemias Chapter 40Extrinsic Nonimmune Hemolytic Anemias Part V. Host Defense and Its Disorders Chapter 41Immunoglobulins and Complement Biology REORGANIZED Chapter 42Normal Phagocyte Structure and Function Chapter 43Eosinophilia, Eosinophil-Associated Diseases, and the Hypereosinophilic Syndrome Chapter 44Disorders of Phagocyte Function and Number Chapter 45Disorders of Lymphocyte Function Chapter 46Histiocytic Disorders Chapter 47Lysosomal Storage Diseases: Perspective and Principles Chapter 48Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases Chapter 49The Spleen and Its Disorders Chapter 50Basophils, Mast Cells, and Systemic Mastocytosis Part VI. Hematologic Malignancies Chapter 51Cytogenetics and Neoplasia Chapter 52The Molecular Basis of Neoplasia Chapter 53Pharmacology and Molecular Mechanism of Action or Resistance of Antineoplastic Agents: Current Status and Future Potential Chapter 54Principles of Radiation Oncology for Hematologic Malignancies NEW Chapter 55Clinical Application of Cytokines Chapter 56Biologic Response Modifiers NEW Chapter 57Pathobiology of Acute Myeloid Leukemia Chapter 58Clinical Manifestations of Acute Myeloid Leukemia Chapter 59Therapy for Acute Myeloid Leukemia Chapter 60Acute Myeloid Leukemia in Children Chapter 61Pathobiology of Acute Lymphoblastic Leukemia Chapter 62Clinical Manifestations of Acute Lymphoblastic Leukemia Chapter 63Treatment of Childhood Acute Lymphoblastic Leukemia Chapter 64Acute Lymphoblastic Leukemia in Adults Chapter 65Myelodysplastic Syndrome Chapter 66Polycthemia Vera Chapter 67Chronic Myelogenous Leukemia Chapter 68Agnogenic Myeloid Metaplasia Chapter 69Primary Thrombocythemia Chapter 70Myelodysplastic Syndromes and Myeloproliferative Syndromes in Children Chapter 71Pathobiology of Non-Hodgkin Lymphomas Chapter 72Pathology and Histogenesis of Hodgkin Disease Chapter 73Hodgkin Disease: Clinical Manifestations, Staging, and Therapy Chapter 74The Pathologic Basis for the Classification of Non-Hodgkin Lymphomas Chapter 75Clinical Manifestations, Staging, and Treatment of Non-Hodgkin Lymphoma Chapter 76Malignant Lymphomas in Childhood Chapter 77Chronic Lymphocytic Leukemia Chapter 78Hairy Cell Leukemia Chapter 79Cutaneous T-Cell Lymphomas Chapter 80AIDS-Related Lymphomas Chapter 81Multiple Myeloma and Other Plasma Cell Disorders Chapter 82Amyloidosis Chapter 83Atypical Immune Lymphoproliferations Chapter 84Clinical Approaches to Infections in the Compromised Host Chapter 85Nutritional Support of Patients with Hematologic Malignancies Chapter 86Psychosocial Aspects of Hematologic Disorders Chapter 87Pain Management and Antiemetic Therapy in Hematologic Disorders Chapter 88Palliative Care NEW Chapter 89Indwelling Access Devices Chapter 90Late Complications of Hematologic Disease and Their Therapies NEW Part VII. Transplantation Chapter 91Transplant for Bone Marrow Failure and Autoimmune Disorders NEW Chapter 92Hematopoietic Stem Cell Transplantation for Genetic Diseases and Immune Deficiencies NEW Chapter 93Results of Allogeneic Stem Cell Transplantation for Malignant Disorders Chapter 94Results of Autologous Stem Cell Transplantation for Malignancies Chapter 95Unrelated Donor Stem Cell Transplantation Therapy Chapter 96Placental and Umbilical Cord Blood Transplantation Chapter 97Preparative Regimens for Stem Cell Transplantation Chapter 98Graft-versus-Host Disease and Graft-versus- Leukemia Effect Chapter 99Achievement of Tolerance NEW Chapter 100Graft Engineering to Enhance Engraftment, Reduce Graft-versus- Host Disease, and Provide a Graft-versus-Tumor Effect Chapter 101Gene Therapy for Hematologic Disorders Chapter 102Experimental Cell Therapy (include NK-, T-, and dendric cells) Chapter 103Complications After Stem Cell Transplantation Part VIII. Hemostasis and Thrombosis Chapter 104Megakaryocyte and Platelet Structure Chapter 105The Molecular Basis for Platelet Function Chapter 106The Molecular Basis for Platelet Activation Chapter 107The Blood Vessel Wall Chapter 108Molecular Basis of Blood Coagulation Chapter 109Molecular and Cellular Basis of Fibrinolysis Chapter 110Regulatory Mechanisms in Hemostasis: Natural Anticoagulants Chapter 111Clinical Evaluation of Hemorrhagic Disorders: The Bleeding History and Differential Diagnosis of Pupura Chapter 112Laboratory Evaluation of Hemostatic Disorders REORGANIZED Chapter 113Structure, Biology, and Genetics of Factor VIII Chapter 114Biochemistry of Factor IX and Molecular Biology of Hemophilia B Chapter 115Clinical Aspects and Therapy of Hemophilia Chapter 116Inhibitors in Hemophilia Chapter 117Other Clotting Factor Deficiencies Chapter 118Quantitative and Qualitative Disorders of Fibrinogen Chapter 119Structure, Biology, and Genetics of von Willebrand Factor Chapter 120Clinical Aspects of and Therapy for von Willebrand Disease Chapter 121Vitamin K: Metabolism and Disorders Chapter 122Inhibitors of Blood Coagulation Chapter 123Disseminated Intrvascular Coagulation Chapter 124Hemostatic Defects Associated with Dysproteinemias Chapter 125Disorders of Coagulation and Platelets in the Neonate Chapter 126Hypercoagulable States Chapter 127Venous Thromboembolism Chapter 128Arterial Thromboembolism Chapter 129Anticoagulation and Thrombolytic Therapy REORGANIZED Chapter 130Immune Thrombocytopenic Purpura, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura Chapter 131Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome Chapter 132Thrombocytopenia Due to Platelet Destruction and Hypersplenism Chapter 133Hereditary Disorders of Platelet Function Chapter 134Acquired Disorders of Platelet Function Part IX. Transfusion Medicine Chapter 135Human Blood Group Anitgens and Antibodies Part 1: Carbohydrate Determinants Part 2: Protein Determinants Chapter 136Human Platelet Antigens Chapter 137HLA and Neutrophil Antigen and Antibody Systems Chapter 138Principles of Red Blood Cell Transfusion Chapter 139Principles of Platelet Transfusion Therapy Chapter 140Principles of Neutrophil (Granulocyte) Transfusions Chapter 141Transfusion of Plasma Derivatives: Fresh-Frozen Plasma, Cryoprecipitate, Albumin, and Immunoglobulins Chapter 142Intravenous Immunoglobulin NEW Chapter 143Preparation of Plasma-Derived and Recombinant Human Plasma Proteins Chapter 144Transfusion Principles for Congenital Coagulation Disorders Chapter 145Hemapheresis and Cellular Therapy NEW Chapter 146Practical Aspects of Stem Cell Collection Chapter 147Transfusion Reactions Chapter 148Transfusion-Transmitted Diseases Chapter 149Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ Transplantation Part X. Consultative Hematology Chapter 150Hematologic Manifestations of Systemic Disease: Liver and Renal Disease REORGANIZED Chapter 151Hematologic Manifestations of Systemic Disease: Infection, Chronic Inflammation, and Cancer Chapter 152Hematologic Manifestations of Systemic Disease: HIV Infection Chapter 153Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis Chapter 154Hematologic Aspects of Pregnancy Chapter 155Hematologic Manifestations of Childhood Illness Part XI. Special Tests and Procedures Chapter 156Bone Marrow Aspiration and Morphology Chapter 157Automated Analysis of Blood Cells Chapter 158Laboratory Detection of Hemoglobinopathies and Thalassemias Chapter 159Antenatal Diagnosis of Hematologic Disorders Chapter 160Use of Molecular Techniques in the Analysis of Hematologic Diseases Chapter 161Special Imaging Applications in Hematology NEW Chapter 162Coagulation Studies and Their Interpretation NEW