Targets of Treatment in Chronic Inflammatory Bowel Diseases

List of principle authors. Preface. Defining Targets of Treatment by Analysis of Gut Inflammation. 1. State of the Art Lecture: Theories of IBD aetiology from the 1930s to the 1960s; D.B. Sachar. I: Defining Targets by Understanding Aetiopathogenesis of Gut Inflammation. 2. Development of novel drugs for IBD based on molecular targets; S. Schreiber. 3. On the role of innate immunity during mucosal defence and intestinal infections: Are there new therapeutic targets for intervention? S. Bauer. 4. Enteric bacteria: Innocent bystanders, therapeutic targets or vehicles for mucosal delivery of therapeutic molecules? R.B. Sartor. II: Tools for Therapeutic Development. 5. Do animal models always give the right direction for therapy? C.O. Elson, et al. 6. Are cell lines and cultures a good way to develop therapeutic approaches? G. Rogler. 7. Characterization of intestinal barrier function: A putative target for therapeutical modification; M. Gehring, J.-D. Schulzke. III: Alternative Concepts New Targets in the Making. 8. The adipose tissue as a source of proinflammatory signals in Crohn's disease? J.-F. Colombel, et al. 9. Intraluminal targets in Crohn's disease: The possible role of bile acids; A.F. Hofmann. 10. Therapeutic targets in rheumatoid arthritis: Is there a lesson to be learned for gastroenterologists? U. Muller-Ladner. V: General Targets. 11. Interstitial lung diseases and inflammatory bowel diseases: Pathophysiological parallels and differences; J. Muller-Quernheim. 12. A functional genomics approach to study wound repair: The roles of activin and S100A8/S100A9 in the healing process; I.S. Thorey, et al. 13. Neuroendocrine-immune interactions: A novel therapeutic approach? S.M. Collins. Aims of Treatment in Daily Practice. 14. State of the Art Lecture: Evolution of treatment from the 1930s to the end of the 1980s; P. Riis. 15. Extraintestinal manifestations Important target of treatment or just an expression of disease activity? F. Tavarela-Veloso. 16. What do patients want? Defining treatment goals from the other side; J. Minchew. 17. Measuring health-related quality of life: Fad, fantasy or fruitful exercise? E.J. Irvine. VI: Specific Targets. 18. Specific targets Diarrhea; W. Kruis, et al. 19. Abdominal pain as a therapeutic target in inflammatory bowel disease; H.J.F. Hodgson. 20. Strictures in IBD Are there differential indications for surgery or endoscopic dilation? G.van Assche, et al. 21. Spectrum of inflammatory bowel diseases related arthropathy: are there differential treatment options? M.de Vos. VII: Special Problems. 22. Magnetic resonance imaging (MRI) in patients with IBD: A new method to assess disease activity; S. Feuerbach, et al. 23. Cancer prevention in inflammatory bowel disease as a treatment goal; A. Ekbom. VIII: Quality of Care. 24. The impact of age and social environment on therapeutic concepts; C. Gasche. 25. Avoiding side effects: A therapeutic goal? W.J. Sandborn. Index.