Heat Shock Proteins and Inflammation -

Heat Shock Proteins and Inflammation

Willem Van Eden (Herausgeber)

Buch | Hardcover
XIII, 280 Seiten
2003 | 2003
Springer Basel (Verlag)
978-3-7643-6932-3 (ISBN)
171,19 inkl. MwSt
Heat shock proteins (HSP) have received ample interest by immunologistsover recent years. Initially they were found to be dominantlyimmunogenic microbial antigens. The connection with inflammation wasestablished when it was uncovered that T cells specific for theseantigens have a crucial role in the induction and regulation ofexperimental arthritis. Since then, the raised presence of immunity toHSPs in virtually all conditions of inflammation, including autoimmunediseases, transplant rejection and atherosclerosis, has emphasised thecritical significance of immunity to HSPs in inflammatory diseases.

HSP60 and the regulation of inflammation: Physiological and pathological.- Heat shock proteins and suppression of inflammation.- Heat shock proteins in immune response.- Heat shock protein-mediated activation of innate immune cells.- Eukaryotic HSP60: A "danger signal" for T- and natural killer cells.- Heat shock proteins and experimental arthritis.- Heat shock proteins and reactive arthritis.- The development of immune therapy with HSP60 for juvenile idiopathic arthritis.- Heat shock proteins and rheumatoid arthritis.- Heat shock proteins for immunotherapy of rheumatoid arthritis.- Immunity to heat shock proteins and atherosclerosis.- Chaperonins: Chameleon proteins that influence myeloid cells.- Heat shock protein receptors, functions and their effect on monocytes and dendritic cells.- Heat shock protein expression in transplanted kidney.- Mycobacterial heat shock proteins and the bovine immune system.- Microbial infection generates pro-inflammatory autoimmunity against the small heat shock protein alpha B-crystallin and provides the fuel for the development of multiple sclerosis.- HSP60-peptide interference with CD94/NKG2 receptors.

Erscheint lt. Verlag 24.10.2003
Reihe/Serie Progress in Inflammation Research
Zusatzinfo XIII, 280 p.
Verlagsort Basel
Sprache englisch
Maße 155 x 235 mm
Gewicht 795 g
Themenwelt Studium Querschnittsbereiche Infektiologie / Immunologie
Schlagworte Activation • antibodies • Arthritis • atherosclerosis • Autoimmune diseases • Bacteria • behcet disease • Diseases • encephalomyelitis • Entzündung • immune response • immune system • immunity • immunotherapy • inflammation • Influence • juvenile arthritis • kidney • Macrophages • Mycobacteria • proteins • Regulation • Rheumatoid Arthritis • Schock (med.) • Schock (Medizin) • T Cells • tuberculosis vaccines • type I diabetes • Wärme
ISBN-10 3-7643-6932-9 / 3764369329
ISBN-13 978-3-7643-6932-3 / 9783764369323
Zustand Neuware
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