Insular Epilepsies

Dang Nguyen is Professor of the Department of Neuroscience at Université de Montréal, neurologist/epileptologist at the Centre Hospitalier de l'Université de Montréal (CHUM) and clinician-scientist at the CHUM Research Center, Montreal, Canada. Jean Isnard is an Epileptologist in the Department of Functional Neurology and Epilepsy, Neurological Hospital, Hospices Civils de Lyon, Lyon, France; and Claude Bernard University Lyon 1, Lyon, France. Philippe Kahane is a neurologist and neurophysiologist, Hospital Practioner and University Professor at Grenoble-Alpes University and Hospital, Grenoble, France. He is the Director of the Grenoble Hospitalo-University Federation of Clinical Neurosciences and is in charge of the clinical epileptology program.

Foreword François Mauguière; 1. A brief history of insular cortex epilepsy François Dubeau; Part I. The human insula: Viewpoint from Epileptology: 2. Anatomy of the insula Alexander Hammers; 3. Vascularization of the insula: Key points for safe epilepsy surgery Naoki Ikegaya and Masaki Iwasaki; 4. Structural connectivity of the insula Jimmy Ghaziri, Phillip Fei, Laurent Petit and Dang Khoa Nguyen; 5. Functional connectivity of the insula Leila Ayoubian, Jean-Didier Lemaréchal and Olivier David; 6. Interoceptive integration in the primate insular cortex Henry C. Evrard; Part II. The spectrum of epilepsies involving the insula: 7. Clinical presentation of opercular-insular epilepsy in adults Laurence Martineau, Dang Khoa Nguyen and Jean Isnard; 8. Clinical presentation of operculo-insular epilepsy in children Michael S. Duchowny, Delphine Taussig and Petia S. Dimova; 9. Are painful seizures specific to insular epilepsy? Alexandra Montavont, Laure Mazzola, Genevieve Demarquay and Jean Isnard; 10. The role of the insula in temporal lobe epilepsy and temporal lobe 'plus' epilepsies Carmen Barba and Philippe Kahane; 11. Insular-origin seizures with frontal presentation Koichi Hagiwara, Steve A. Gibbs, Sylvain Rheims and Lino Nobili; 12. The role of the insula in SUDEP Samden Lhatoo and Nuria Lacuey; Part III. Non-invasive investigation of insular epilepsy: 13. Non-invasive electrophysiological investigations in insular epilepsy Raluca Pana, Laurence Martineau, Ismail Mohamed, Tao Yu and Dang Khoa Nguyen; 14. Structural imaging of insular epilepsy Andreas V. Alexopoulos; 15. PET and SPECT in insular epilepsy Francine Chassoux and Jean-Paul Soucy; 16. Neuropsychology of insular epilepsy Olivier Boucher, Sallie Baxendale, Alain Bouthillier and Dang Khoa Nguyen; Part IV. Invasive investigation of insular epilepsy: 17. Invasive investigation of insular epilepsy: Indications and preplanning Philippe Ryvlin and Fabienne Picard; 18. Invasive investigation of insular epilepsy: Surgical techniques Alexander G. Weil and Francesco Cardinale; 19. Qualitative interpretation of intracranial EEG in insular epilepsy Lorella Minotti, Rinki Singh, Guillaume Martin, Dominique Hoffmann, Laurence Martineau and Philippe Kahane; 20. Quantitative intracranial EEG signal analysis in insular epilepsy Fabrice Bartolomei, Nicolas Roehri, Francesca Pizzo and Rinki Singh; 21. Electrical stimulation of the human insular cortex Laure Mazzola, Jean Isnard and François Mauguière; Part V. Surgical management of insular epilepsy: 22. Insular epilepsy surgery: Surgical techniques and experience of various centers Alain Bouthillier, Stephan Chabardes, Massimo Cossu and Jorge Gonzalez-Martinez; 23. SEEG-guided radiofrequency thermocoagulation of insular epileptic foci Alice Rucar, Jean Isnard and Marc Guenot; 24. Neurostimulation for the treatment of insular cortex epilepsy Patricia C. Dugan and Barbara C. Jobst; 25. Laser interstitial thermal therapy (LITT) for insular epilepsy Azeem A. Rehman, Dave F. Clarke and Mark R. Lee.