Blood and Marrow Transplantation Long Term Management -

Blood and Marrow Transplantation Long Term Management

Survivorship after Transplant
Buch | Hardcover
416 Seiten
2021 | 2. Auflage
Wiley-Blackwell (Verlag)
978-1-119-61269-8 (ISBN)
165,80 inkl. MwSt
Hematopoietic cell transplantation (HCT) provides curative therapy for a variety of diseases. Over the past several decades, significant advances have been made in the field of HCT, to the point where HCT has become an integral part of treatment modality for a variety of hematologic malignancies and some nonmalignant diseases. HCT remains an important treatment option for a wide variety of hematologic and nonhematologic disorders, despite recent advances in the field of immunologic therapies. Factors driving this growth include expanded disease indications, greater donor options (expanding unrelated donor registries and haploidentical HCT), and accommodation of older and less fit recipients.

The development of less toxic pretransplant conditioning regimens, more effective prophylaxis of graft-versus-host disease (GVHD), improved infection control, and other advances in transplant technology have resulted in a rapidly growing number of transplant recipients surviving long-term free of the disease for which they were transplanted. The changes over decades in the transplant recipient population and in the practice of HCT will have almost inevitably altered the composition of the long-term survivor population over time. Apart from an increasingly older transplant recipient cohort, the pattern of transplant indications has shifted from the 1990s when chronic myeloid leukemia made up a significant proportion of allo-HCT indications. Changes in cell source, donor types, conditioning regimens, GVHD prophylaxis, and supportive care have all occurred, with ongoing reductions in both relapse and non-relapse mortality (NRM) have been demonstrated.

These patients have increased risks for a variety of late complications, which can cause morbidity and mortality. Most long-term survivors return to the care of their local hematologists/oncologists or primary care physicians, who may not be familiar with specialized monitoring and management of long complications after HCT for this patient population. As HCT survivorship increases, the focus of care has shifted to the identification and treatment of long-term complications that may affect quality of life and long-term morbidity and mortality.

Preventive care as well as early detection and treatments are important aspects to reducing morbidity and mortality in long-term survivors after allo-HCT. This second edition, »Blood and Marrow Transplantation Long-Term Management: Survivorship after Transplant«, provides up-to-date information about diagnosis, screening, treatment, and long-term surveillance of long-term survivors after HCT.

Bipin N. Savani is Professor of Medicine and Director of Long-Term Transplant and Survivorship Clinic at Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, TN, USA.

Andre Tichelli is Professor Emeritus of Hematology, Division of Hematology, University Hospital of Basel, Switzerland.

List of contributors


Section 1 Late effects concepts


1 Introduction


Bipin N Savani and Andre Tichelli


2 International Blood and Marrow registries - trends on long-term data collection


Rachel Phelan, Jakob Passweg, Helen Baldomero, Minako Iida, Yoshiko Atsuta, Shinichiro Okamoto, Mahmoud Aljurf, Feras Alfraih, and Bronwen Shaw


3 Long-term transplant clinic setup


Andre Tichelli, Bipin Savani, Shahrukh K Hashmi, Navneet S Majhail, and Alicia Rovo


4 Telemedicine in patient care of long-term survivors


Catherine Lee, Mihkaila Wickline, and Mary Flowers


5 Long-term follow-up calendar


Andre Tichelli, Bipin N Savani, Shahrukh K Hashmi, Navneet S Majhail, and Alicia Rovo


6 Late effects after allogeneic hematopoietic stem cell transplantation


Shahrukh Hashmi and Yoshihiro Inamoto


7 Late effects after autologous hematopoietic stem cell transplantation


Rajshekhar Chakraborty and Betty Hamilton


8 Long-term follow-up of children


Paul Carpenter


9 Graft-versus-host disease and GvHD-associated late effects


David Michonneau, Aurelien Sutra-del-Galy, and Gerard Socie


10 Screening and prevention guidelines for hematopoietic cell transplant survivors


Neel S Batt, J Douglas Rizzo, and Navneet S Majhail


11 Biology of survivorship after BMT


Smita Bhatia


Section 2 Specific late effects


12 Secondary malignancies


Aurelien Sutra-del-Galy, David Michonneau, and Gerard Socie


13 Anti-infective prophylaxis, immunization and prevention of late infectious complications


Per Ljungman


14 Seasonal virus infections in recipients and exposure to family members


Nosha Farhadfar, Zeina Al-Mansour, and John Wingard


15 Monitoring and management of hepatitis B, C, and HIV infection before and after transplantation


Enric Carreras and Montserrat Rovira


16 Skin chronic graft-versus-host disease


Attilio Oliveri and Andrea Bacigalupo


17 Ocular complications


Alicia Rovo, Andre Tichelli, and Yoshihiro Inamoto


18 Oral and dental complications


Hildegard Greinix


19 Thyroid late complications


Juliana Matthews, Leslee Matheny, and Shubhada Jagasia


20 Pre-transplant considerations in gender, reproductive, and sexual health


Dana Shanis, Jeanne Murphy, Kate Debiec, Betty K Hamilton, Shawna Boyle, and Pamela Stratton


21 Post-transplant considerations in gender, reproductive, and sexual health


Jeanne Murphy, Dana Shanis, Kate Debiec, Betty K Hamilton, Shawna Boyle, and Pamela Stratton


22 Fertility issues, fertility preservation, and pregnancy outcome in long-term survivors


Alicia Rovo, Alison W Loren, Andre Tichelli, and Nina Salooja


23 Sexual dysfunction in long-term survivors


Rebecca Hunter, Sarah Thilges, Janna Gordon, Kristy Luke, Karla Cavazos, Emilee Moeke, Colleen Bruen, and Sunita Natha


24 Non-infectious pulmonary late complications


Ayman O Soubani


25 Cardiac and arterial complications


Alicia Rovo and Andre Tichelli


26 Cardiovascular risk factors


Kimberley Doucette and Minoo Battiwalla


27 Gastrointestinal complications


Sumona Bhattacharya, Steven Pavletic and Theo Heller


28 Hepatic complications


Christy Ann L Gilman Christopher Koh, Steven Pavletic, and Theo Heller


29 Renal complications


Insara Jaffer Sathick, and Sangeeta Hingorani


30 Post-Transplantation Bone Disease


Christine Ducan


31 Neurological late complications


Enrico Maffini


32 Neurogognitive dysfunction


David Buchbinder


33 Psychological distress


Anna Barata, Aasha I Hoogland and Heather SL Jim


34 Persistent chronic fatigue


Sandy Mitchell


35 Social issues


Sanghee Hong and Navneet Majhail


36 Health-related quality of life in adult and pediatric survivors


Lori Wiener, Jenny Hoag, and Tamryn Gray


Section 3 Supportive care and patients reported outcome


37 Immunosuppressive agents and monitoring in long-term survivors


Katie Culos and Katie Gatwood


38 Nutritional support and nutritional supplementation


Shigeo Fuji


39 Daily routines and healthy lifestyle guidelines


Melissa Logue


40 Prevalent psychosocial adjustment issues and solutions: lifestyle and social challenges


Katrina Stokes


41 Complementary and alternative medicine in HSCT


Ibrahim N Muhsen, Bipin N Savani, and Shahrukh Hashmi


42 Impact of adherence in outcome of long-term survivors


Corien Eeltink and Annika Kisch


43 Prominent role of allied health professionals


Catherine E Lucid


44 Patient reported outcome


Helene Schoemans


45 Caregivers of long-term survivors


Angela Moreschi Woods


46 Patient's perspective: memory of a recovered lymphomaniac


Michael Brown


Appendix 1 Commonly used transplant-related medications in long-term survivors


Katie Culos and Katie Gatwood


Appendix 2 The eGVHD App


Helene Schoemans


Index

Erscheinungsdatum
Verlagsort Hoboken
Sprache englisch
Maße 178 x 254 mm
Gewicht 1506 g
Einbandart gebunden
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Chirurgie
Medizinische Fachgebiete Innere Medizin Hämatologie
Medizin / Pharmazie Medizinische Fachgebiete Notfallmedizin
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Schlagworte Hämatologie • Hematology • Knochenmarktransplantation • Medical oncology • Medical Science • Medizin • medizinische Onkologie • Transplantation • Transplantationen
ISBN-10 1-119-61269-1 / 1119612691
ISBN-13 978-1-119-61269-8 / 9781119612698
Zustand Neuware
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