Liver Disorders in Childhood

A comprehenisve account of modern paediatric hepatology which aims to assist clinicians in detecting hepatobiliary disorders at the earliest possible stage and provide effective management. This expanded edition includes summaries of recent research findings.

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A comprehensive account of modern paediatric hepatology which aims to assist clinicians in detecting hepatobiliary disorders at the earliest possible stage and in providing the most effective management. All medical aspects of hepatobiliary disorders are covered, with sufficient details of surgical procedures to indicate their possible pathophysiological consequences and complications. Extensive revision of this text covers recent developments in cellular and molecular biology, inborn errors of metabolism, viral hepatitis and immunology. The place of advances in ultrasonography, radiology, endoscopy and laparoscopy are considered and developments in etiology, prevention, pathophysiological mechanisms, diagnosis and treatment in every area are detailed. Some chapters have been expanded or completely rewritten, such as that on liver transplantation, and new chapters added on alpha-1 antitrypsin deficiency, chronic hepatitis, autoimmune chronic active hepatitis and sclerosing cholangitis. Throughout the text, latest research findings are summarised and areas in which further studies are urgently required are highlighted.