Female Sexual Pain Disorders

The Editors Andrew T. Goldstein is Director of the Centers for Vulvovaginal Disorders and a Clinical Professor at George Washington University School of Medicine, Washington, DC, USA. Caroline F. Pukall is Professor and Director of the Sex and Relationship Therapy Service, Department of Psychology, Queen's University, Kingston, Ontario, Canada. Irwin Goldstein is Director of Sexual Medicine at Alvarado Hospital, Director of San Diego Sexual Medicine, and Clinical Professor of Surgery at University of California San Diego, CA, USA.

List of Contributors ix

1 Nosology of Pelvic Pain and Vulvodynia 1
Tami S. Rowen and Andrew T. Goldstein

2 The Prevalence and Relevance of Vulvodynia 9
Ruby H.N. Nguyen

3 Pathophysiology of Pain: Peripheral and Central 15
Melissa A. Farmer

4 The Role of Inflammation in Vulvodynia 31
David C. Foster

5 Neuroproliferative Processes in Vulvodynia 43
Jacob Bornstein and Eilam Palzur

6 Pelvic Floor Muscle Dysfunction and Structural Processes in Vulvodynia 53
Pamela Morrison and Kaitlyn Parrotte

7 Hormonal Causes of Dyspareunia 63
Andrew T. Goldstein

8 Genetic Factors in Vulvodynia 69
Steven S. Witkin and Iara M. Linhares

9 Central Factors in Vulvodynia 75
Ursula Wesselmann and Peter P. Czakanski

10 Comorbidities of Vulvodynia 81
Nancy A. Phillips and Gloria Bachmann

11 Psychosocial Factors in Vulvodynia 87
Sophie Bergeron and Natalie O. Rosen

12 Pain Assessment in Vulvodynia: Self-report Measures 97
Caroline F. Pukall and Stéphanie C. Boyer

13 Pain Assessment in Vulvodynia: Objective Measures 103
Linda McLean and Caroline F. Pukall

14 An Overview of the Evaluation of Dyspareunia, Vulvovaginal Pain, and Pelvic Pain 115
Andrew T. Goldstein

15 Vulvoscopic Evaluation of Vulvodynia 125
Ashley G. Winter and Rachel S. Rubin

16 Pelvic Floor Assessment of Vulvodynia 133
Stephanie Prendergast and Elizabeth Akincilar

17 Psychosocial Assessment of Vulvodynia 143
Sophie Bergeron and Natalie O. Rosen

18 Neurological Assessment in Genito-pelvic Pain 151
Irwin Goldstein and Barry R. Komisaruk

19 Diagnostic and Treatment Algorithm for Women with Vulvodynia and Sexual Pain Disorders 157
Andrew T. Goldstein

20 Medical Treatment of Inflammatory-associated Provoked Vestibulodynia 163
Susan Kellogg-Spadt

21 Treatment of Neuroproliferative-associated Provoked Vestibulodynia with Topical Medications 171
Candace Brown

22 Hormonal Factors in Women’s Sexual Pain Disorders 177
Irwin Goldstein

23 Physical Therapy Treatment of Pelvic Floor Dysfunction 185
Amy Stein, Dee Hartmann, and Kaitlyn Parrotte

24 Treatment of Vulvodynia with Pelvic Floor Muscle Relaxants/Injections 193
Andrea M. Avondstondt and Michael S. Ingber

25 Psychosocial Treatments for Vulvodynia 201
Sophie Bergeron and Natalie O. Rosen

26 Complementary and Integrative Health Approaches for the Treatment of Vulvodynia 209
Judith M. Schlaeger and Meryl J. Alappattu

27 Vulvar Vestibulectomy 219
Andrew T. Goldstein

28 Vulvovaginitis 227
Jack D. Sobel and Paul Nyirjesy

29 Vulvar Dermatoses as a Cause of Dyspareunia 239
Gail R. Goldstein and Andrew T. Goldstein

30 Genitourinary Syndrome of Menopause: The Role of Estrogens and Androgens 251
Rachel S. Rubin and James A. Simon

31 Female Genital Cutting 261
Crista E. Johnson-Agbakwu and Jasmine Abdulcadir

32 Interstitial Cystitis/Bladder Pain Syndrome 273
Esther Han, Laura N. Nguyen, Lauren Tennyson, Larry T. Sirls, and Kenneth M. Peters

33 The Basic Science of Endometriosis 289
Paul Yong

34 Endometriosis Treatment 301
Catherine Z. Wu, Jordan Klebanoff, and Gaby Moawad

35 Chronic Pelvic Pain 313
Juliana Taney and Frank Tu

36 Postpartum Genito-pelvic Pain 323
Jill M. Krapf and Erryn Tappy

37 Pudendal Neuralgia 333
Richard P. Marvel

38 Cancer and Genito-pelvic Pain 349
Beverly Long and Areta Bojko

39 Irritable Bowel Syndrome and Female Sexual Dysfunction 359
Sarah Cigna

40 Inability to Experience Penetrative Vaginal Intercourse: Evaluation and Management 367
Elke D. Reissing

41 Chronic Clitoral Pain and Clitorodynia 375
Stephanie M. Radke and Colleen K. Stockdale

42 Generalized Unprovoked Vulvodynia 381
Ariel Arbel and Ahinoam Lev-Sagie

43 Persistent Genital Arousal Disorder 387
Robyn Jackowich, Caroline F. Pukall, and Irwin Goldstein

44 Fibromyalgia and Female Sexual Pain Disorders 395
Mollie Rieff, Sarah Bedell, and Sarah Cigna

45 Animal Models of Genito-pelvic Pain 403
Megan L. Falsetta, Ronald W. Wood, and David C. Foster

46 Patient Advocacy for Vulvodynia 411
Phyllis Mate and Lisa Goldstein

47 Practical Aspects of Establishing a Vulvovaginal Pain Center 417
Sue W. Goldstein

48 Editors’ Wish List 423
Andrew T. Goldstein, Caroline F. Pukall, and Irwin Goldstein

Index 429